[Thyroid status in anemic pregnant women under conditions of endemic goiter]. / Sostoianie shchitovidnoi zhelezy u beremennykh s anemiei v usloviiakh zobnoi éndemii.

Anemia is a highly prevalent condition among pregnant women in the Republic of Kazakhstan. The causes of this anemia are not quite clear, as is the problem of resistance of this type of anemia to therapy with iron preparations. The authors propose that this may be explained by the fact that many regions of the Republic are foci of endemic goiter, because tentative studies indicate a relationship between endemic goiter and hypothyrosis. The present study was aimed at examination of the thyroid status in pregnant women suffering from anemia in the town of Alma-Ata, a region endemic for goiter. Altogether 120 anemic pregnant women were examined, 60 of these with goiter and 60 without it. Control group consisted of 20 healthy pregnant women. Clinical and ultrasonic examinations, puncture biopsy of the thyroid, measurements of blood levels of TTH, total and free triiodothyronine and thyroxin, thyroxin-binding globulin, as well as of peripheral blood red cell counts, levels of hemoglobin, serum iron, assessment of total iron-binding capacity of the serum and saturation coefficient, were carried out. Healthy pregnant women from a focus of endemic goiter were found to represent a group at risk of anemia in the third pregnancy trimester. In anemic pregnant women endemic goiter aggravated anemia. Chronic iodine deficiency is conductive to formation in pregnant women of subclinical hypothyrosis whose severity increased in the presence of anemia, more so if anemia is paralleled by goiter.

[The incidence of recurrences and metastases of cancer of the corpus uteri and the reasons for their occurrence]. / Chastota retsidivov i metastazov raka tela matki i prichiny ikh vozniknoveniia.

The paper discusses the frequency of recurrences and metastases of endometrial carcinoma in 246 treated cases. Recurrences and metastases were identified in 41 (16.7% +/- 2.4) patients. A relationship between said frequency, on the one hand, and tumor size, extent of invasion through the myometrium and tumor differentiation, on the other, was established.

[Determination of the volume of surgical intervention in cancer of the corpus uteri]. / Opredelenie ob"ema khirurgicheskogo vmeshatel'stva pri rake tela matki.

Clinical, cytologic, histologic and X-ray procedures were used in examining 120 patients with endometrial carcinoma. The results of pre- and intraoperative determination of clinical stage were compared in 65 cases of uterine extirpation with appendages and lymphadenectomy. Errors in preoperative identification of the extent of tumor expansion were made in 9 cases (13.8 +/- 4.3%). It was found that determinations of the site and expansion of tumor make the case for hystero-cervical-angiolymphography whereas identification of tumor pattern and degree of cell differentiation--for cytologic and histologic assays.