RESUMO
We report a case of significant pulmonary hemorrhage developing shortly after commencing ticagrelor and aspirin therapy and requiring coronary artery bypass grafting to safely cease the antiplatelet therapy. Lung biopsy findings were consistent with drug-induced lung injury. Clinicians should be aware of this significant adverse event with this drug class.
Assuntos
Síndrome Coronariana Aguda/terapia , Adenosina/análogos & derivados , Hemoptise/etiologia , Pneumonia/induzido quimicamente , Adenosina/efeitos adversos , Adenosina/uso terapêutico , Aspirina/efeitos adversos , Aspirina/uso terapêutico , Biópsia , Ponte de Artéria Coronária , Diagnóstico Diferencial , Hemoptise/diagnóstico , Humanos , Pulmão/diagnóstico por imagem , Pulmão/patologia , Masculino , Pessoa de Meia-Idade , Inibidores da Agregação Plaquetária/efeitos adversos , Inibidores da Agregação Plaquetária/uso terapêutico , Pneumonia/complicações , Pneumonia/diagnóstico , Antagonistas do Receptor Purinérgico P2Y/efeitos adversos , Antagonistas do Receptor Purinérgico P2Y/uso terapêutico , Ticagrelor , Tomografia Computadorizada por Raios XRESUMO
In brief Bicycling can be a viable alternative to jogging for cardiovascular fitness. However, little research demonstrates the level of intensity and duration necessary to produce a cardiovascular training effect. This study gives the results of seven weeks of bicycle interval training on college women and men aged 20 to 24. There were four workouts per week of progressively increasing intensity and duration. The experimental group improved Vo2 max by almost 6 ml·kg-1· min-1. There were no injuries during the training period.