RESUMO
Epidemiological and BCG vaccination background and clinicoroentgenological signs of tuberculosis were analysed with reference to epidemiological and BCG vaccination background in 177 infants. In infants tuberculosis was represented primarily by intrathoracic lymph node tuberculosis running as infiltrative, tumorous and minor. Disseminated tuberculosis and meningitis occurred as a rule within the first year of life. The disease most frequently arose due to tuberculosis contact. More than half of the children from the infection foci developed complications. In conditions of massive exogenic superinfection BCG vaccination fails to prevent infection and further progression of the disease.
Assuntos
Tuberculose/diagnóstico , Adulto , Fatores Etários , Pré-Escolar , Humanos , Lactente , Recém-Nascido , Radiografia , Tuberculose/diagnóstico por imagem , Tuberculose/transmissão , Tuberculose dos Linfonodos/diagnóstico , Tuberculose dos Linfonodos/diagnóstico por imagem , Tuberculose dos Linfonodos/transmissão , Tuberculose Meníngea/diagnóstico , Tuberculose Meníngea/diagnóstico por imagem , Tuberculose Meníngea/transmissãoRESUMO
As shown by the analysis of tuberculosis forms in 27 infants under 1 year of age (group 1) and 150 infants of older age (group 2), the involvement of the intrathoracic lymph nodes holds the first place among tuberculosis forms encountered in infants. Severe infection (tuberculous meningitis, disseminated tuberculosis) occurred more frequently in group 1. The authors emphasize epidemiological significance of contacts with tuberculous patients. To decrease infant tuberculosis incidence rate, it is of much more importance to make early diagnosis in the adults, to give infants preventive treatment, chemoprophylaxis in particular, than to perform BCG vaccination under conditions of close contacts with tuberculous subjects.
Assuntos
Vacina BCG , Tuberculose/prevenção & controle , Vacinação , Adulto , Fatores Etários , Humanos , Incidência , Lactente , Recém-Nascido , Fatores de Risco , Teste Tuberculínico , Tuberculose/diagnóstico , Tuberculose/epidemiologia , Tuberculose/transmissãoRESUMO
The results of indirect hemagglutination with phosphatide and protein antigens in children with different manifestations of primary Tb infection point to a high diagnostic potential of the serological method. Specially designed and tested diagnostic preparations made of TB and BCG vaccine strain tuberculin can perfect the diagnosis of tuberculosis and determination of its activity. Employment of the erythrocytic diagnosticum with BCG tuberculin extends the potential of detecting postvaccinal complications in children immunized with BCG vaccine.