[Computed tomographic anatomy of the salivary glands in the cat]. / Computertomographische Anatomie der Speicheldrüsen der Katze.

OBJECTIVE: The aim of the study was to define anatomical characteristics of the feline salivary glands in cross-sectional images obtained by unenhanced computed tomography (CT) and to describe landmarks for a reliable identification. MATERIAL AND METHODS: Heads of adult normocephalic cats without indications of cephalic disease were examined. Cats were included in the prospective part of the study when examined no later than 1 hour post mortem (n = 16). In the retrospective part of the study, previous CT-studies were evaluated (n = 25). The results of both groups were evaluated separately. Initially, the possibility of identifying and delineating the salivary glands from the surrounding tissue was assessed. Anatomical structures of the head were then defined as landmarks. Dimensions and density (Hounsfield units, HU) of the salivary glands were determined based on transversal and reconstructed sagittal images. RESULTS: In total, 94.3% of the parotid glands, 90.7% of the mandibular glands and 96.8% of the zygomatic glands could be delineated. The remaining salivary glands could not be identified. Anatomical landmarks, including the external ear canal, the musculus (M.) masseter, the M. pterygoideus medialis and the bulbus oculi facilitated the identification. Comparing the size of the salivary glands of both groups revealed differences (measured lateromedially and rostrocaudally) in size of ≤   2 mm. The definable salivary glands varied significantly in their density. The mean density of the glandula (Gl.) parotis was 65 HU, of the Gl. mandibularis 62 HU and of the Gl. zygomatica 57 HU. The comparisons of densities of both sides of the glands did not show statistically significant differences. CONCLUSIONS: The large salivary glands (Gl. parotis and Gl. mandibularis) and the Gl. zygomatica of the cat can be reliably identified in CT-images. CT landmarks and data regarding the size and density of each gland could be gathered. The remaining minor salivary glands could not be delineated accurately. The difference in depicting the glands can be explained mainly by a lack of contrast with the surrounding tissue.

[Options for the reduction of magnetic susceptibility artifacts caused by implanted microchips in 0.5 Tesla magnetic resonance imaging]. / Möglichkeiten zur Reduktion von Suszeptibilitätsartefakten durch Mikrochips bei Untersuchungen im 0,5-Tesla-Magnetresonanztomographen.

OBJECTIVE: Microchips contain ferromagnetic materials, which lead to severe focal image interferences when performing magnetic resonance imaging (MRI). Very small animals are particularly prone to these susceptibility artifacts, which may hinder analysis of the neck-region MRI image. We investigated the impact of sequence type on the artifact's size and determined the optimal imaging parameters to minimize these artifacts. Furthermore, the minimum distance between the microchip and the spinal canal required to assess the spinal structures should be determined. MATERIAL AND METHODS: Investigations were performed on the cadavers of 26 cats and two dogs using a low-field MRI System (field strength 0.5 Tesla). To quantify susceptibility artifacts, several sequence types (spin echo, turbo-spin echo (TSE), gradient echo) and imaging parameters (echo time (TE), voxel volume, frequency direction) were systematically varied. Additionally, computed tomography imaging was performed to determine the distance between the microchip and the spinal canal. RESULTS: The size of the artifact was smallest with T1-weighted TSE sequences. A short TE (10 ms) and a small voxel size (acquisition matrix 256 x 256 pixels, field of view 160 mm, slice thickness 2 mm) significantly reduced artifact size. Furthermore, it could be shown that by changing the frequency- and phase-encoding direction, the shape and orientation of the maximum dimension of the artifact could be influenced. Even when using an optimized T1-weighted TSE sequence, it was impossible to evaluate the spinal cord when the distance between the microchip and the center of the spinal canal was < 19  mm. CONCLUSION AND CLINICAL RELEVANCE: In MR studies of the cervical spine of small dogs and cats, microchips can cause severe susceptibility artifacts. Because of the small distance between the microchip and the spinal structures, spinal evaluation may be limited or impossible. The investigations demonstrated that the adjustment of sequence parameters helps to significantly minimize artifact size and shape. The greatest reduction in artifact size was achieved by using a T1-weighted TSE sequence.

[Sonographic measurement of soft-palate thickness and comparison with the measurement by computed tomography]. / Sonographische Messung der Gaumensegeldicke beim Hund im Vergleich zur computertomographischen Messung.

OBJECTIVE: The aim of this study was to measure the thickness of the soft palate at specific locations in normocephalic dogs using sonography and computed tomography (CT), and to subsequently compare the two different methods. MATERIAL AND METHODS: A total of 15 normocephalic dogs were examined under general anesthesia. The CT was performed while patients were in a sternal recumbent position, their mouth held open by placing their upper jaw on a positioning device. Dorsal recumbency together with submental and midsagittal positioning of the transducer were chosen for sonography. Measurements were made in both sonographic and reconstructed sagittal CT images. Two measuring points (MP) were defined for measuring the cranial and the middle part of the soft palate (MP1: 1 cm caudal to the transition from the hard to the soft palate; MP2: at the origin of the dorsal pharyngeal muscles). It was investigated whether repeated procedures with one measuring method provided consistent values and, furthermore, whether the two different measuring methods (sonography and CT) provided comparable data. RESULTS: The data acquired by repeat measurements within one method corresponded very well. However, the data provided by the two different measurement methods showed varying results for the first measuring point and was even greater for the second measuring point. Sonography overestimated the measurements obtained by CT by up to 0.26 cm for MP1 and up to 0.79 cm for MP2. CONCLUSION: Due to the significant discrepancies in their results, the two measurement methods are not interchangeable. Sonography showed good reliability for repeat measurements. Consequently, the variable values between CT and sonography appeared to result from differing examination conditions. Sonography may be a rapid and non-invasive diagnostic tool to measure soft palate thickness if the applied method proves to be applicable in clinical practice.

[Comparison of projection radiography and computed tomography for the detection of pulmonary nodules in the dog and cat]. / Vergleich von Projektionsradiographie und Computertomographie zur Detektion pulmonaler Rundherde bei Hund und Katze.

OBJECTIVE: The aim of our study was to evaluate the value of projection radiography as a standard screening method for the detection of lung nodules compared to computed tomography (CT). Furthermore, we attempted to describe the reasons that might lead to a failed detection of pulmonary nodules in radiography. MATERIALS AND METHODS: From dogs and cats which were diagnosed in CT (multislice CT) with nodular changes in the lung pattern we selected radiographs (projection radiography with soft copy reading) in at least two projection planes produced in the same timeframe as the CT images. Exclusion criteria were nodules > 3 cm and homogenously calcified nodules (osteomata). A total of 70 animals (50 dogs and 20 cats) met the inclusion criteria. RESULTS: In 43 animals (61%), nodular changes had already been detected using radiography and were then confirmed by the results of the computed tomography. In detail, 32 of 50 dogs (64%) and 11 of 20 cats (55%) showed nodular lesions in the radiographs. In cats, undetected nodules were often accompanied by highly changed lung opacities, resulting in a poor contrast of the lung. In dogs the reasons for a failed detection of lung nodules were relatively equally distributed to several causes. Interestingly, small nodule size itself was not the predominant reason for missing the nodules in radiographs. CONCLUSION AND CLINICAL RELEVANCE: In general, radiography still plays an important role as a screening method for the detection of nodular lung lesions. However, one needs to be aware, that a quite high percentage of nodular lung changes can be missed in radiographs. The overall detection rate in this study was 61%. Furthermore, we showed that plane radiographs are of poor diagnostic value when concurrent problems exist which lead to increased lung opacity.

The vacuum phenomenon in intervertebral disc disease of dogs based on computed tomography images.

OBJECTIVES: Vacuum phenomenon is suspected to be indicative of disc degeneration and subsequent herniation. The objective of this study was to assess the reliability of vacuum phenomenon for identification of herniated discs causing neurological signs. Prevalence of vacuum phenomenon and influencing factors in dogs with disc herniation were determined. METHODS: Retrospective review of computed tomography scans from dogs with suspected disc herniation for the presence of gas within intervertebral disc space with subsequent comparison of vacuum phenomenon and herniated disc as confirmed by surgery. Subgroups were created (chondrodystrophic, non-chondrodystrophic and unknown classification) to analyse prevalence and influencing factors (age, breed and gender) for vacuum phenomenon and agreement with herniated disc. RESULTS: Prevalence of vacuum phenomenon in all dogs, chondrodystrophic, non-chondrodystrophic dogs and those with unknown classification was 19·8, 14·9, 35·7 and 24·5%, respectively. Corresponding correlation rate between vacuum phenomenon and herniated disc was 64, 67, 40 and 82%. Prevalence of vacuum phenomenon was significantly higher in nonchondrodystrophic dogs (P=0·04). Age was the only factor influencing prevalence of vacuum phenomenon (P=0·04). CLINICAL SIGNIFICANCE: In dogs with intervertebral disc disease, vacuum phenomenon is a frequent but inconsistent finding. Although helpful to identify degenerated discs, it is not suitable to identify currently herniated disc with sufficient accuracy.

[Multiphasic contrast-enhanced CT: correlation of the peak attenuation in the aorta abdominalis and portal vein with easily detectable clinical parameters]. / Multiphasen-Kontrastcomputertomographie: Korrelation der Anreicherungskurven in Aorta abdominalis und Vena portae mit einfach klinisch messbaren Parametern.

OBJECTIVE: The diagnostic value of a multiphase CT strongly depends on the correct timepoints of analysis. Therefore, we investigated whether the peak attenuation time in the aorta and portal vein are predictable using easily detectable clinical parameters. Regression equations were developed that enable an approximate prediction of these scan times. MATERIAL AND METHODS: Contrast dynamic CT was performed in 39 anaesthetised dogs of different breeds. The heart rate at the onset of the examination, the age and the body weight were documented. The contrast agent Imeron 300® was injected into a cephalic vein at 3 ml/s with 600 mg iodine/kg body weight using an automatic injector and a dynamic axial CT was started at the same time. The peak enhancement time in the aorta (pETA) and portal vein (pETP) were measured. RESULTS: The mean pETA was 24.5 ± 8.6 seconds and the mean pETP was 43.6 ± 13.4 seconds. There was a strong correlation (r = 0.92) between pETA and body weight in combination with the heart rate, and a moderate correlation (r = 0.66) between pETP and body weight in combination with the age. The regression equation was: pETA = 12.23 + 0.61 body weight - 0.07 heart rate. The time between pETA and pETP was 8-24 seconds in 34 animals. CONCLUSION: To plan the arterial peak the authors recommend the use of the established regression equations based on the statistical results or alternatively bolus tracking to plan the arterial peak. When it is planned to examine the portal venous peak, an interscan duration of 8-14 seconds is recommended.

Rhinolithiasis in two miniature dogs.

This case report describes two dogs, a Chihuahua and a Pekingese each with rhinolithiasis. Both dogs were presented with chronic nasal obstruction and discharge. Rhinoliths were noted on computed tomography scans in both animals, and removed via endoscopic extraction in one case and laser-assisted endoscopic surgery in the other. The stone from the Chihuahua comprised calcium carbonate. A potential exogenous nidus in the form of plant material was identified in the Pekingese. To the authors' knowledge, this is the first report of rhinolithiasis in veterinary medicine.

[Liver abscess in a dog. A case report]. / Leberabszess bei einem Hund. Ein Fallbericht.

The presented case report describes diagnostic and therapy of a liver abscess in a male Golden Retriever dog. The dog was adversely affected by fever, apathy, and vomitus. Diagnostic imaging including radiography, sonography and computed tomography, revealed an abscess-forming lesion of 10 × 5 cm in the left middle liver lobe with detectable multiple gas accumulation within the lesion. The surgical therapy included lobectomy with adjacent omentopexy. Four days after the operation the dog was discharged in a good general condition and with physiological body temperature. Detecting multiple gas accumulation in circular, inhomogeneous lesions by sonography allowed confirmation of the diagnosis. Surgical removal of the affected liver lobe led to recovery of the patient. In human medicine, less invasive methods are preferred, e.g. percutaneous drainage and alcoholization of the lesion. Exclusive medicamentous therapy yields the worst outcome in humans.

Diagnostic yield and adverse effects of MRI-guided free-hand brain biopsies through a mini-burr hole in dogs with encephalitis.

BACKGROUND: The diagnosis of encephalitis is usually presumptive based on MRI, cerebrospinal fluid analysis, or both. A definitive diagnosis based on histopathology, however, is required for optimizing treatment strategies. OBJECTIVE: To investigate the diagnostic yield and adverse effects of minimally invasive brain biopsies in dogs with encephalitis. ANIMALS: Seventeen dogs with suspected encephalitis, based on MR imaging and cerebrospinal fluid analysis. METHODS: Retrospective study. Minimally invasive, free-hand brain biopsy specimens were taken from forebrain lesions through a 4-mm burr hole using a Sedan side-cutting needle. Routine histopathological examination was performed. The adverse effects were assessed by MRI evaluations after biopsy procedure (12/17) and by sequential neurological examinations. RESULTS: The overall diagnostic yield with regard to a specific type of encephalitis was 82%. Encephalitis was evident in an additional 12%, but a specific disease could not be determined. There were no deaths caused by the biopsy procedure itself, but the indirect case fatality rate was 6%. Morbidity was 29%, including stupor, seizures, tetraparesis, hemiparesis, ataxia, and loss of conscious proprioception. All these signs resolved within 3-14 days. CONCLUSIONS AND CLINICAL IMPORTANCE: Minimally invasive brain biopsy in dogs with suspected encephalitis leads to a definite diagnosis in the majority of dogs, allowing for a specific treatment. The advantages of a definite diagnosis outweigh potential case fatality rate and temporary neurological deficits.

[Magnetic resonance imaging and ultrasonography in dogs and cats with ocular and orbital diseases. Part 1: Ocular diseases]. / Kernspintomographische und sonographische Untersuchungen bei Hunden und Katzen mit intraokulären und orbitalen Erkrankungen. Teil 1: Intraokuläre Erkrankungen.

OBJECTIVE: This two-part study describes the clinical usefulness and value of ultrasound and magnetic resonance imaging (MRI) in dogs and cats with ocular (n=30) and orbital diseases (n=31). MRI and ultrasonography characteristics are described in single cases with ocular and orbital disease. MATERIAL AND METHODS: Ultrasonography and MRI were performed in 15 dogs and 15 cats with intraocular neoplasia or intraocular inflammatory disease. RESULTS: In all patients with intraocular neoplasia, sonography revealed masses with increased echogenicity and fairly uniform echotexture, thus allowing the tentative diagnosis of an intraocular tumour. In these cases, MRI often proved to be a valuable diagnostic tool in showing the complete extent of intraocular lesion. An additional benefit of MRI was seen in the tissue characterization of tumours based on MRI signal characteristics and pattern of contrast enhancement. Discreet intraocular inflammatory alterations, in particular to the anterior and posterior segment of the eyeball, were more clearly shown by ultrasound than by MRI. Neoplasia could be excluded and inflammatory disease was successfully diagnosed using MRI due to the different image sequences with or without contrast medium administration. Traumatic ruptures of the lens capsule and the globe after trauma were depicted more clearly with MRI. CONCLUSIONS AND CLINICAL RELEVANCE: When opacity of the anterior eye segment is present, various intraocular changes can be quickly diagnosed by ultrasound with high accuracy, without requiring anaesthesia of the patient. MRI of the globe allows differentiation of diverse pathologies, gives detailed information of infiltration in orbital structures and the exact degree of ocular lesions after trauma. This additional evidence often makes it easier to predict the correct prognosis and choose the best therapy.

[Magnetic resonance imaging of the temporomandibular joint in dogs and cats. Effect of different coils on image quality]. / Magnetresonanztomographische Untersuchung des Kiefergelenks von Hund und Katze. Einfluss unterschiedlicher Spulen auf die Bildqualität.

OBJECTIVE: In magnetic resonance imaging (MRI) the image quality is considerably affected by the coil used, particularly when small structures are examined. The purpose of this study was to determine which coil provides the best scanning results for imaging of the temporomandibular joint (TMJ) of dogs and cats. MATERIAL AND METHODS: MRI investigations were performed using a standard human knee coil and an 8-cm-diameter surface coil with a low-field MRI-system (field strength 0.5 T). TMJs of two dogs and two cats were examined. The scan protocol consisted of T1-weighted spin echo (T1W/SE), T2-weighted turbo spin echo (T2W/TSE), a proton density-weighted sequence (PDW) (slice thickness: 3 mm each), and gradient echo sequences (slice thickness: 1-1.5 mm) in the sagittal plane. Three observers independently compared the features "contrast resolution", "bone structure", "spatial resolution", and "signal-to-noise ratio" (SNR) using a 5-point scale. Investigators were blinded with respect to the coils used. RESULTS: Approximately 50% of the images obtained by the use of the surface coil were rated superior in comparison with the knee coil in terms of the features "contrast resolution", "bone structure", and "spatial resolution". In approximately 50% of the MRI-images no differences in the ratings were seen. With respect to the criterion "signal-to-noise ratio" 90% of the images acquired with the surface coil were rated better. In 5% of the images an identical quality was recorded. The surface coil proved to be superior both in dogs and cats. CONCLUSIONS AND CLINICAL RELEVANCE: Display quality of small structures of the TMJ is dependent on the spatial resolution of the MR images. Therefore, a dedicated coil and a small field of view (FOV) should be used. Results reveal that low-field MRI is able to display subtle anatomic structures of the TMJ in dogs and cats. In principle, the results can be transmitted to other MRI-systems. However, to generate valid scan protocols it is necessary to adapt scan parameters and coil selection specifically.

[Computed tomography imaging of the temporomandibular joint in dogs and cats. Effects of different scan parameters on image quality]. / Computertomographische Darstellung des Kiefergelenks von Hund und Katze. Beeinflussung der Bildqualität durch unterschiedliche Aufnahmeparameter.

OBJECTIVE: Temporomandibular joints (TMJs) of dogs and cats were examined with multislice computed tomography (MSCT) using different technical scan parameters in order to investigate their impact on image quality. Another aspect was to analyze whether size differences of the TMJ affect the display of small joint structures. MATERIAL AND METHODS: The TMJs of two dogs and two cats were examined using MSCT. Scan parameters were varied including tube current, scan matrix, resolution mode, slice thickness, and reconstruction increment. Three observers being blinded with respect to the used scan parameters independently assessed the image quality in terms of "contrast resolution", "bone structure", "spatial resolution", "evaluation of the joint space", and "artefacts" according to a 4-point scale. RESULTS: The criteria "spatial resolution" and "evaluation of the joint space" emphasize the influence of the size of the TMJ. The image quality of the TMJ of the dogs was evaluated superior (by 0.5 to 1.5 points higher graded) compared to the smaller ones of the cats. In terms of "spatial resolution" and "bone structure" the images of an ultra high resolution technique achieved a higher evaluation level (scoring one point superior) compared to the images created by a high resolution protocol. The tube current did not significantly influence the image quality in any of the pictures. CONCLUSIONS AND CLINICAL RELEVANCE: The display quality of small structures of the TMJ is dependent on the spatial resolution of the CT images. Therefore, a thin slice collimation, a small field of view, and a high resolution reconstruction matrix should be used. Under those aspects subtle alterations of bone structure of the TMJ can be reliably detected. The soft tissue structures of the TMJ can not be visualized with MSCT in small animals. In principle, the results can be applied to any other MSCT-scanner. However, adjustments of the technical parameters may be still necessary.

[Effects of a neuroleptic analgesia with acepromazine on the blood perfusion of the canine kidney. Examination using the sonographic recordable blood circulation parameters of resistance index and pulsatility index]. / Auswirkung einer Neuroleptanalgesie mit Acepromazin auf die Durchblutung der Niere beim Hund. Überprüfung anhand der sonographisch erfassbaren Durchblutungsparameter Resistance-Index und Pulsatilitätsindex.

OBJECTIVE: Kidney failure after anaesthesia constitutes a serious clinical complication. A number of patients suffer from compensated kidney insufficiency, which may be transformed into an acute kidney insufficiency through additional stress, such as an operation and anaesthesia. The aim of the present study was to investigate the effects of a neurolept analgesia with acepromazine on sonographically accessible blood perfusion parameters. MATERIAL AND METHODS: Following anaesthesia with acepromazine/l-methadone (0.1 mg/kg BW acepromazine, 0.5 mg/kg BW l-methadone) a sonographic examination of the left kidney was performed in 19 clinically healthy foxhound and beagle dogs. Every 5 minutes resistance index and pulsatility index as well as invasive blood pressure were measured and digitally recorded. RESULTS: Within 5 minutes after induction of anaesthesia a transient increase of the mean arterial blood pressure occurred. After 10 minutes the blood pressure decreased to the initial value and remained essentially constant to the end of the investigation. Resistance index and pulsatility index showed a similar behaviour: After a small initial decrease during the first 5 minutes both parameters displayed a significant increase. This rise was very pronounced up to approximately 15 minutes and then flattened significantly until the end of the test period after 30 minutes. The values corresponded to those found in vessel stenosis. CONCLUSION AND CLINICAL RELEVANCE: Due to the described changes this type of anaesthesia should not be used in dogs with nephropathy, even though the results of this experimental study might not be necessarily transferable to the clinical patient.

[Sonographic examination of the soft palate in dogs]. / Sonografische Untersuchung des weichen Gaumens beim Hund.

PURPOSE: The aim of this study was to characterize the normal sonographic anatomy of the soft palate in dogs. MATERIALS AND METHODS: The study was performed on seven canine heads via a submental and intraoral approach. The detected anatomical structures were then reexamined via a submental approach in a water bath. Each anatomic layer was subsequently dissected starting with the submental layers and working towards the soft palate. After every preparation a sonographic examination was carried out. RESULTS: Differentiation between the soft palate and the surrounding oropharyngeal tissue can be effectively achieved. Using the submental approach, the transition between hard palate and soft palate as well as the middle section of the soft palate were distinguished from other oropharyngeal structures in all cases. Visualization of the caudal part of the velum and evaluation of the echogenicity of the soft palate were difficult and not always possible. In the two brachycephalic dogs of the study, it was challenging to distinguish the soft palate from the surrounding tissue. CONCLUSION: The sonographic appearance of the canine soft palate in cadavers was described in this study. The submental approach allows differentiation between intraoral structures. Evaluation of the echogenicity and length of the soft palate is limited.

Concentration of platelets and growth factors in canine autologous conditioned plasma.

OBJECTIVES: To report the concentration of blood cells and selected growth factors in canine autologous conditioned plasma (ACP). METHODS: The density of blood cells in whole blood (WB), ACP and standard plasma preparation (SP) of 10 healthy mature dogs was determined. In both ACP and SP, the concentration of insulin-like growth factor-1 (IGF-1), epidermal growth factor, vascular endothelial growth factor, platelet-derived growth factor-AA, platelet-derived growth factor-AB, platelet-derived growth factor-BB, transforming growth factor-ß1 (TGF-ß1), and transforming growth factor-ß2 was measured using the ELISA technique. In another ten dogs, ACP was prepared using an ultra-soft spinning protocol, and again blood cell density was compared to that obtained in WB. RESULTS: The density of platelets in ACP was significantly higher than that in SP (p = 0.0002), but there was not any significant difference between ACP and WB, nor between WB and ACP prepared using softer centrifugations. Interestingly, only for IGF-1, PDGF-BB, and TGF-ß1 could reliable measurements be obtained, showing a significant increase in PDGF-BB and TGF-ß1 concentrations in ACP compared to SP (p = 0.001, p = 0.0028). Regarding IGF-1 content, there was not any significant difference between ACP and SP. CLINICAL SIGNIFICANCE: Canine ACP prepared according to the manufacturer's recommendations, or by using a softer spin does not show the same specifications as human ACP, which shows a doubling in platelet count compared to WB. Even though canine ACP has a similar number of platelets per injected volume and consequently, probably the same amount of injected growth factors than WB, application of canine ACP would not be associated with the proinflammatory potential reported for WB, as it is almost free of erythrocytes and nucleated cells.

Cartilage thickness and split-line pattern at the canine humeral trochlea.

OBJECTIVE: To characterise the humeral trochlea in middle to large breed dogs in respect to split-line pattern and cartilage thickness. METHODS: In 15 paired cadaveric elbow joints of mature dogs (>20 kg body weight) collagen network orientation of the hyaline cartilage of the humeral trochlea was visualised using a traditional split-line technique in which a dissecting needle dipped in India ink was inserted into the cartilage (n = 10). Cartilage thickness was measured radiographically on osteochondral plugs harvested at four representative locations within the joint surface of the humeral trochlea (n = 15). RESULTS: The joint surface of the humeral trochlea showed a distinct pattern of centripetally oriented split-lines with less pronounced or even absent split-lines caudo- proximally towards the olecranon fossa. Median cartilage thickness at the canine humeral trochlea was 0.51 mm (interquartile range: 0.42 - 0.61 mm). Centrally, at the region where osteochondrosis lesions commonly occur in middle to large breed dogs, the median cartilage thickness was 0.55 mm (interquartile range: 0.48 - 0.62 mm). CLINICAL SIGNIFICANCE: When focusing on anatomical joint resurfacing while performing osteochondral transplantation at the canine humeral trochlea, transplants should be implanted such that their split-lines are oriented centripetally. Hyaline cartilage thickness of transferred grafts should be in the range of half a millimetre to optimally match the situation at the canine humeral trochlea.

[Geometry and function of the dog nose: how does function change when form of the nose is changed?]. / Geometrie und Funktion der Hundenase: Wie ändert sich die Funktion, wenn die Form verändert wird?

Nasal airflow resistance in brachycephalic dogs is significantly elevated compared to normal dogs. LaserAssisted TurbinEctomy (LATE)-surgery as well as xylometazolin were shown to reduce pathologically increased intranasal airway resistance in brachycephalic dogs by approximately 50 %. Impulse oscillometry provides a reliable and sensitive method to examine intranasal stenoses in the canine nose. Acoustic rhinometry allows assessment of changes in cross sectional area and volume of the canine nasal cavity.

[Brachycephaly in dog and cat: a "human induced" obstruction of the upper airways]. / Brachyzephalie bei Hund und Katze: eine "menschengemachte" Obstruktion der oberen Atemwege.

Selective breeding for exaggerated features caused in many brachycephalic dog and cat breeds virtually a loss of the nose, with serious anatomical and functional consequences. In addition to respiratory and olfactory tasks, in dogs the nose is of vital importance for thermoregulation. As obligatory nose breathers, dogs suffer far more than humans when their nasal ventilation is restricted. An open discussion in the broad public has to motivate authorities and kennel clubs to recognize extreme brachycephalic breeding as seriously affecting animal health and welfare.