[Clinical validation of a method for biological demonstration of low radiation levels by the densitometric-geometric parameters of peripheral blood lymphocytes]. / Klinicheskaia aprobatsiia metoda bioindikatsii malykh urovnei radiatsii po denito-geometricheskim parametram limfotsitov perifericheskoi krovi.

Karyometric analysis of blood lymphocytes of persons, exposed to low levels of radiation (up to 25 rem) during elimination of the consequences of the Chernobyl accident, has shown changes of lymphocyte densitometric-geometric parameters, characteristic for radiation exposure, observed in 188 of 294 examinees. The meaning of these statistically significant changes is the following: percentage of the level of large lymphocytes is on the decrease whereas that of average and small ones is on the decrease. There is also a parallel rise of values of the area and perimeter of a lymphocyte nuclear section. The above shifts were observed against a background of normal indices of the absolute number and a relative content of blood lymphocytes. Karyometric analysis of lymphocytes indicated signs of radiation exposure 1-33 mos. after irradiation at small doses. Cytogenetic verification of diagnosis has shown sensitivity of the karyometric method of biological demonstration [correction of bioindication], which can be recommended as an additional diagnostic test in chronic exposure to low levels of radiation for retrospective assessment.

[Assessment of the degree of severity of radiation lesions in dogs using densitometric-geometric parameters of the blood lymphocytes]. / Otsenka stepeni tiazhesti luchevogo porazheniia sobak po densito-geometricheskim parametram limfotsitov krovi.

Changes in densitometric-geometric parameters of lymphocyte nuclei of dog peripheral blood detected at early times (6 and 24 H) following gamma irradiation with 2.5 and 6.0 Gy are given a composite description. Using densitometric-geometric parameters the authors have developed an algorithm allowing for a 90% accuracy in the classification of objects according to the severity of radiation affection.

[The use of image recognition methods in evaluating the degree of severity of radiation injury]. / Primenenie metodov raspoznavaniia obrazov pri otsenke stepeni tiazhesti luchevogo porazheniia.

The possibility of application of mathematical methods of the image recognition theory for the estimation of radiation damage severity (RDS) is grounded. The application of the method for the RDS estimation according to densito-geometrical parameters of the peripheral blood lymphocytes is described. The decisive rules for the estimation of the RDS within the feature space are developed. The obtained statistically valid linear discriminant functions possess a high descriptive and prognostic power.

[Automatic television analyzer of micro-objects for morphometric research on blood cells]. / Avtomaticheskii televizionnyi analizator mikroob"ektov dlia morfometricheskikh issledovanii kletok krovi.

A method of karyometric analysis of blood cells and the hardware for its realization are described. The method is based on TV object image analysis, and involves measuring videosignal parameters.

[Possible use of television image analysis for measuring the volume and surface area of irregularly shaped nuclei]. / O vozmozhnosti ispol'zovaniia analiza televizionnogo izobrazheniia dlia izmereniia ob"ema i poverkhnosti iader nepravil'noi formy.

A use of the TV image for measuring volumes and squares of blood cell nuclei irregular in shape is considered. The linear correspondence has been detected between the volumetric-spatial structure of the object and the shape of the respective video-signal, this correspondence being mathematically proved. The measuring of parametres of video-signal may be informative of the object's shape.