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Fitoterapia ; 74(7-8): 682-5, 2003 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-14630173

RESUMO

The n-hexane-dichloromethane (1:1) extract of the roots of Onosma argentatum and the methanol extract (partitioned between water and chloroform, ethyl acetate and n-butanol, respectively), of the underground parts (roots and rhizomes) of Rubia peregrina were tested in vitro for their antioxidant and antimicrobial activities. The highest antioxidant activity (98%) was observed at 0.1% concentration for the roots of O. argentatum. It was 96% at 0.25% concentration on the ethyl acetate fraction of R. peregrina. O. argentatum extract was effective on Staphylococcus aureus, Bacillus subtilis and Escherichia coli. The ethyl acetate and chloroform fractions of R. peregrina were effective on S. aureus and E. coli, respectively. These two species did not have any antifungal activity.


Assuntos
Anti-Infecciosos/farmacologia , Antioxidantes/farmacologia , Boraginaceae , Fitoterapia , Extratos Vegetais/farmacologia , Rubia , Anti-Infecciosos/administração & dosagem , Anti-Infecciosos/uso terapêutico , Antioxidantes/administração & dosagem , Antioxidantes/uso terapêutico , Bacillus subtilis/efeitos dos fármacos , Escherichia coli/efeitos dos fármacos , Humanos , Testes de Sensibilidade Microbiana , Extratos Vegetais/administração & dosagem , Extratos Vegetais/uso terapêutico , Raízes de Plantas , Staphylococcus aureus/efeitos dos fármacos
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