RESUMO
In a group of 246 patients with dyskaryotic cervical smears, 144 had 4-quadrant punch biopsies (4Q), while 102 had Lugol's iodine applied to the cervix before punch biopsies were taken from abnormally stained areas (ISD) to determine whether the latter will improve the chances of taking biopsies from areas of cervical intraepithelial neoplasia (CIN). In the ISD group, 66 (64.7%) of the patients had histological confirmation of CIN compared to 56 (38.9%) of those in the 4Q group. Follow-up smears in patients with benign histological findings revealed dyskaryosis in 54.7% and 25% in the 4Q and ISD groups respectively, which is suggestive of a higher false-negative rate in the 4Q group. It is suggested that where facilities for colposcopically-directed biopsy of the cervix is unavailable, patients with abnormal smears should have Lugol's iodine applied before punch cervical biopsies are taken.
Assuntos
Iodetos , Coloração e Rotulagem , Displasia do Colo do Útero/patologia , Neoplasias do Colo do Útero/patologia , Esfregaço Vaginal , Biópsia por Agulha/efeitos adversos , Biópsia por Agulha/métodos , Colposcopia , Técnicas Citológicas , Reações Falso-Negativas , Feminino , Seguimentos , Técnicas Histológicas , Humanos , Estadiamento de Neoplasias , Índice de Gravidade de Doença , Triagem/métodos , Displasia do Colo do Útero/diagnóstico , Displasia do Colo do Útero/epidemiologia , Neoplasias do Colo do Útero/diagnóstico , Neoplasias do Colo do Útero/epidemiologia , Hemorragia Uterina/epidemiologia , Hemorragia Uterina/etiologiaRESUMO
Within the period August 1984 to January 1987, 209 needle aspirates of breast lumps were examined cytologically. One hundred and forty-four smears had histological confirmation. The diagnostic accuracy of fine needle aspiration cytology for malignancy is 79% in this study, with a specificity of 97%. The role of fine needle aspiration cytology, as a useful diagnostic tool and a necessary adjunct to clinical examination in the assessment of breast lumps is discussed.
