1.
Dalton Trans
; 46(5): 1539-1545, 2017 Jan 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28091659
RESUMO
The reaction of 2-alkynyl anilines with catalytic amounts of B(C6F5)3 (5 mol%) resulted in the formation of 2-substituted indoles according to an intramolecular hydroamination in good to excellent yields. Reaction intermediates as well as products were characterized by NMR spectroscopy and by X-ray crystallography. The domino hydroamination/hydrogenation sequence allowed the efficient synthesis of tetrahydroquinoline 8 in good yield.