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1.
Am J Otolaryngol ; 37(3): 186-94, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27178505

RESUMO

PURPOSE: To investigate the difference in survival and complication outcomes between patients with a clinically and radiologically N0 neck who received an elective neck dissection at the time of salvage total laryngectomy compared to those who had salvage total laryngectomy alone. MATERIALS AND METHODS: A retrospective chart review was performed on 125 salvage total laryngectomy patients who were clinically and radiologically N0 preoperatively. Performance of an elective neck dissection and other factors were tested for associations with various postoperative complications, disease-free survival, and overall survival. RESULTS: Ninety-eight patients underwent elective neck dissection, of which ten had positive nodal pathology. Elective neck dissection was not significantly associated with complications or survival outcomes. Positive nodal disease was associated with worse disease-free and overall survival on multivariate analysis. CONCLUSIONS: In patients with clinically and radiologically N0 necks undergoing salvage total laryngectomy, an elective neck dissection can provide prognostic information but does not appear to be significantly associated with increased complications or improved survival.


Assuntos
Carcinoma de Células Escamosas/cirurgia , Neoplasias Laríngeas/cirurgia , Laringectomia , Esvaziamento Cervical , Complicações Pós-Operatórias/epidemiologia , Terapia de Salvação , Adulto , Idoso , Idoso de 80 Anos ou mais , Carcinoma de Células Escamosas/mortalidade , Carcinoma de Células Escamosas/patologia , Intervalo Livre de Doença , Feminino , Humanos , Neoplasias Laríngeas/mortalidade , Neoplasias Laríngeas/patologia , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Estudos Retrospectivos , Taxa de Sobrevida , Resultado do Tratamento
2.
Int Forum Allergy Rhinol ; 3(12): 1021-4, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24343990

RESUMO

BACKGROUND: The objective of this case series was to report what is to the best of our knowledge the first reports of nasopharyngeal and soft palate pseudomeningoceles tracking submucosally from the sphenoid sinus. METHODS: Analysis of cases through medical records. RESULTS: Two cases of middle-aged male patients presented to our tertiary care university teaching hospital for recurrent meningitis and a history of cerebrospinal fluid (CSF) rhinorrhea. Both were found to have pseudomeningoceles distant from the sphenoid sinus. One was tracking to the mucosa of the Eustachian tube, and the other to the dorsum of the soft palate. Both were found to be tracking submucosally from the sphenoid sinus, to the vidian canal, to the lateral nasopharyngeal wall, to their respective locations at the Eustachian tube and dorsum of the soft palate. CSF closure was performed with a transnasal endoscopic repair using the pedicled nasoseptal flap for 1 patient and Alloderm for the other, both with successful cessation of CSF rhinorrhea. CONCLUSION: We present these cases of distant spontaneous CSF leaks. We review the literature and discuss case management.


Assuntos
Rinorreia de Líquido Cefalorraquidiano/cirurgia , Tuba Auditiva/cirurgia , Meningocele/cirurgia , Palato Mole/cirurgia , Seio Esfenoidal/cirurgia , Adulto , Rinorreia de Líquido Cefalorraquidiano/etiologia , Colágeno , Humanos , Imageamento por Ressonância Magnética , Masculino , Meningocele/complicações , Meningocele/diagnóstico , Retalhos Cirúrgicos , Resultado do Tratamento
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