1.
Carbohydr Res
; 434: 18-26, 2016 Nov 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27518204
RESUMO
Ten new triterpene glycosides, stryphnosides G-P (1-10), were isolated from the pericarps of Stryphnodendron fissuratum (Legminosae). The structures of 1-10 were determined based on spectroscopic analyses, including various two-dimensional NMR spectroscopic techniques, and the results of hydrolytic cleavage. The sugar moiety attached to C-3 of the aglycone of 4, 5, and 7-10 is composed of five or six monosaccharides, of which the terminal α-l-arabinosyl unit has a 1C4 conformation. Compounds 2 and 5 differ from the other isolates in having an α-l-rhamnosyl unit at the C-21 hydroxy group. The cytotoxic activity of 1-10, stryphnosides A-F (11-16), and their aglycones (1a, 11a, 14a, and 16a) against HL-60 cells was also examined.