RESUMO
OBJECTIVE: Fetal echogenic bowel (FEB) is a soft marker found on second trimester sonography. Our main aim was to determine the outcome of infants who presented with FEB and secondarily to identify additional sonographic findings that might have clinical relevance for the prognosis. DESIGN: We reviewed all pregnancies in which the diagnosis FEB was made in our Fetal Medicine Unit during 2009-2010 (N=121). We divided all cases into five groups according to additional sonographic findings. Group 1 consisted of cases of isolated FEB, group 2 of FEB associated with dilated bowels, group 3 of FEB with one or two other soft markers, group 4 of FEB with major congenital anomalies or three or more other soft markers, and group 5 consisted of FEB with isolated intrauterine growth restriction (IUGR). RESULTS: Of 121 cases, five were lost to follow-up. Of the remaining 116 cases, 48 (41.4%) were assigned to group 1, 15 (12.9%) to group 2, 15 (12.9%) to group 3, 27 (23.2%) to group 4, and 11 (9.5%) to group 5. The outcome for group 1 was uneventful. In group 2 and 3, two anomalies, anorectal malformation and cystic fibrosis, were detected postnatally (6.7%). In group 4, mortality and morbidity were high (78% resp. 22%). Group 5 also had high mortality (82%) and major morbidity (18%). CONCLUSIONS: If FEB occurs in isolation, it is a benign condition carrying a favourable prognosis. If multiple additional anomalies or early IUGR are observed, the prognosis tends to be less favourable to extremely poor.
Assuntos
Intestino Ecogênico/diagnóstico por imagem , Intestino Ecogênico/mortalidade , Diagnóstico Pré-Natal/métodos , Ultrassonografia Pré-Natal/métodos , Feminino , Humanos , Lactente , Recém-Nascido , Morbidade , Gravidez , Resultado da Gravidez , Segundo Trimestre da Gravidez , Prognóstico , Estudos RetrospectivosRESUMO
Non-Hodgkin lymphoma (NHL) of the female genital tract is extremely rare. We report five cases of NHL, which were collected during an 8-year period from the files of the Department of Pathology at the Onze Lieve Vrouwe Gasthuis, Amsterdam. In these five cases, the NHL was clinically not considered and the genital location was the primary site of presentation.