RESUMO
Eighty-two adult hospitalized patients suffering from respiratory tract infections were treated with cefotiam or cefamandole in an open comparative study. The patients were allocated randomly to one of the two treatments. The recommended dosage regimens (i.m. or i.v.) were used for both groups (cefotiam 1 g b.i.d., cefamandole 1 g t.i.d.). The duration of treatment was 7 to 14 days according to the response of the disease condition. 80 patients were analyzed. The tolerability of both drugs was good and comparable. The clinical and bacteriological efficacy of both drugs was equivalent. The radiological examinations showed a better improvement of the patients treated with cefotiam.
Assuntos
Cefamandol/uso terapêutico , Cefotaxima/análogos & derivados , Infecções Respiratórias/tratamento farmacológico , Adolescente , Adulto , Idoso , Cefamandol/efeitos adversos , Cefotaxima/efeitos adversos , Cefotaxima/uso terapêutico , Cefotiam , Ensaios Clínicos como Assunto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Distribuição Aleatória , Infecções Respiratórias/microbiologiaRESUMO
Pleuropulmonary involvement secondary to Waldenström's macroglobulinaemia is described from a 70-year-old male. The radiographic abnormalities were unilateral pleural effusion and infiltration of the left lower lobe. There were no respiratory symptoms. After removal of the pleural fluid no other therapy was applied.
