RESUMO
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Assuntos
Fármacos Antiobesidade/efeitos adversos , Mielite Transversa/induzido quimicamente , Mielite Transversa/complicações , Leucoencefalopatias/induzido quimicamente , Leucoencefalopatias/complicações , Saúde Pública/tendências , Medicina Preventiva/normas , Testes de Toxicidade/métodos , Testes de Toxicidade/normasAssuntos
Fármacos Antiobesidade/toxicidade , Doenças Desmielinizantes/induzido quimicamente , Leucoencefalopatias/induzido quimicamente , Doenças Desmielinizantes/epidemiologia , Contaminação de Medicamentos , Humanos , Inseticidas/toxicidade , Leucoencefalopatias/epidemiologia , México/epidemiologia , Proteínas do Tecido Nervoso/antagonistas & inibidores , Nitrilas/toxicidade , Resíduos de Praguicidas/toxicidade , Disponibilidade de Medicamentos Via Internet , Inibidores de Proteínas Quinases/toxicidade , Proteínas Tirosina Quinases/antagonistas & inibidores , Espanha/epidemiologia , Texas/epidemiologia , Desacopladores/toxicidadeRESUMO
Non-ischemic cardiomyopathies are defined as either primary or secondary diseases of the myocardium resulting in cardiac dysfunction. While primary cardiomyopathies are confined to the heart and can be genetic or acquired, secondary cardiomyopathies show involvement of the heart as a manifestation of an underlying systemic disease including metabolic, inflammatory, granulomatous, infectious, or autoimmune entities. Non-ischemic cardiomyopathies are currently classified as hypertrophic, dilated, restrictive, or unclassifiable, including left ventricular non-compaction. Cardiovascular Magnetic Resonance Imaging (CMRI) not only has the capability to assess cardiac morphology and function, but also the ability to detect edema, hemorrhage, fibrosis, and intramyocardial deposits, providing a valuable imaging tool in the characterization of non-ischemic cardiomyopathies. This pictorial essay shows some of the most important non-ischemic cardiomyopathies with an emphasis on magnetic resonance imaging features.
RESUMO
Acute toxic leukoencephalopathy can be caused by exposure to many compounds. Reversibility has been described in some cases with prompt recognition and withdrawal of the offending agent. Its association with a thermogenic supplement has never been reported. We describe two such cases in young women taking a commercially available thermogenic dietary supplement who presented with acute neurologic deficits and a common magnetic resonance imaging pattern.