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1.
J Neurooncol ; 76(2): 171-4, 2006 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-16307300

RESUMO

Carcinomatous meningitis (CM) occurs in less than 10% of cancer patients. Although patients frequently present with a focal complaint, multifocal signs are often found following careful neurological examination. The gold standard for diagnosis remains the demonstration of neoplastic cells in the cerebrospinal fluid. Despite the discouraging prognosis, palliative treatment may improve quality of life and lengthen lifespan. We report a patient with known primary carcinoma of the urachus who presented with headaches, nausea, vomiting and ataxia 1 week following resection of a nodular arachnoidal metastasis (indenting the cerebellum). Lumbar cerebrospinal fluid subsequently confirmed carcinomatous meningitis. This is the first reported case of carcinomatous meningitis resulting from metastatic urachal carcinoma.


Assuntos
Adenocarcinoma/patologia , Neoplasias Meníngeas/patologia , Úraco , Neoplasias Urológicas/patologia , Adenocarcinoma/líquido cefalorraquidiano , Adenocarcinoma/secundário , Adulto , Neoplasias Cerebelares/líquido cefalorraquidiano , Neoplasias Cerebelares/patologia , Neoplasias Cerebelares/secundário , Evolução Fatal , Humanos , Neoplasias Pulmonares/líquido cefalorraquidiano , Neoplasias Pulmonares/patologia , Imageamento por Ressonância Magnética , Masculino , Neoplasias Meníngeas/líquido cefalorraquidiano , Neoplasias Meníngeas/secundário , Tomografia Computadorizada por Raios X , Neoplasias Urológicas/líquido cefalorraquidiano
2.
J Child Neurol ; 20(11): 914-5, 2005 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-16417863

RESUMO

An 8-year-old girl complained of decreased hearing and difficulty hearing from her right ear while on the telephone. Pure-tone and speech audiometry, immittance (tympanometry, acoustic reflex thresholds), auditory brainstem response, and transient click-evoked otoacoustic emissions were administered. The results were suggestive of a space-occupying lesion, and the patient was referred to a pediatric neurologist and neurosurgeon. A cerebellar pilocytic astrocytoma was found. The patient's audiologic profile is described, along with implications for pediatric neurologic evaluations.


Assuntos
Astrocitoma/complicações , Neoplasias Cerebelares/complicações , Perda Auditiva/etiologia , Astrocitoma/diagnóstico , Audiometria , Neoplasias Cerebelares/diagnóstico , Criança , Potenciais Evocados Auditivos do Tronco Encefálico , Feminino , Lateralidade Funcional , Humanos
3.
Spine (Phila Pa 1976) ; 29(3): E56-60, 2004 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-14752365

RESUMO

STUDY DESIGN: A case of surgical management of dissociated motor loss after decompression of the cervical spine is reported. OBJECTIVES: To present a rationale for surgical treatment of postdecompressive cervical radiculopathy with an illustrative case example. SUMMARY OF BACKGROUND DATA: The unusual complication of radiculopathy after multilevel cervical decompressive procedures is characterized by pain or dissociated motor weakness of the C5 and C6 nerve roots. Conservative management paradigms, including analgesics and steroids, are the rule, but symptoms often persist for many months. There are currently no reports describing foraminotomy as a means of more rapidly alleviating the symptoms of radicular pain and deltoid and biceps brachii weakness seen in the postoperative setting. METHODS: We present a case of bilateral C5 and C6 radiculopathy following multilevel cervical decompression for cervical spondylotic myelopathy, which we treated with posterior foraminotomies. RESULTS: The patient reported complete resolution of his dermatomal pain and demonstrated rapid improvement in upper extremity strength as compared to traditional conservative treatments. The historical experience and pathogenesis regarding this postoperative complication are reviewed. The rationale of root-specific posterior decompression for this debilitating complication is discussed. CONCLUSIONS: Foraminal decompression of the affected nerve roots as demonstrated here has not been described for postdecompressive dissociated motor loss. Such an approach may offer earlier and more complete relief to patients suffering from this unfortunate complication.


Assuntos
Vértebras Cervicais/cirurgia , Descompressão Cirúrgica/efeitos adversos , Radiculopatia/etiologia , Radiculopatia/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Doenças da Medula Espinal/cirurgia , Osteofitose Vertebral/cirurgia
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