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1.
J Nanosci Nanotechnol ; 21(4): 2351-2359, 2021 04 01.
Artigo em Inglês | MEDLINE | ID: mdl-33500051

RESUMO

The influence of chemically converted GO (graphene oxide) functionalized with APTES (3-aminopropyl-triethoxysilane) and unfunctionalized GO, dispersed in ethanolic solution of TEOS (tetraethyl orthosilicate), on the performances of the mortar samples, such as capillary water absorption and compressive strength was evaluated. The effect of the GO based nanomaterials (GO and GO functionalized with APTES) on the mortar microstructure was investigated by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), Raman spectroscopy and scanning electron microscopy (SEM). The multifunctionality of the mortar brushed with GO based nanomaterials consolidation suspension was proved by the results (i) of the mechanical tests which show an improvement of the compressive strength and (ii) the capillary water absorption results which indicate the decreasing of the water penetration speed. For the mortar samples brushed with GO consolidation suspension, an increase value for the compressive strength of approximately twice compared to the untreated control samples and a decreased value for the capillary absorption water coefficient with one order of magnitude in comparison with the untreated control samples were obtained.

2.
Gynecol Endocrinol ; 28(5): 386-90, 2012 May.
Artigo em Inglês | MEDLINE | ID: mdl-22339181

RESUMO

AIM: To investigate the biochemical and genetic thyroid status in women with preeclampsia by the determination of serum FT3 and FT4 levels in association with D1-C785T genotypes. METHODS: We genotyped using PCR-RFLP methods 50 women with preeclampsia and 50 normotensive pregnant women. RESULTS: FT3 levels (pg/ml, 2.63 ± 0.56 vs. 2.91 ± 1.41) were low, and FT4 levels (ng/dl, 1.11 ± 0.3 vs. 0.88 ± 0.14) were high in women with preeclampsia compared to normal pregnant women. The association with severe preeclampsia was stronger for the homozygous T/T genotype (OR 6.57, p = 0.029). Women with preeclampsia with the D1-T785 mutated allele had lower FT3 levels (pg/ml, 2.31 ± 0.81 vs. 3.04 ± 0.39, p < 0.001), higher FT4 levels (ng/dl, 1.32 ± 0.87 vs. 0.84 ± 0.24, p = 0.009) than women with preeclampsia with the D1-C/C genotype. Significant decrease in serum FT3 levels in positive women with severe preeclampsia compared to women negative for this genetic variation (pg/ml, 1.59 ± 0.74 vs. 2.77 ± 0.23, p = 0.003) was observed. Women with severe preeclampsia, positive for the mutated T785 allele, delivered at a significantly lower gestational age (31.75 ± 3.69 vs. 38.66 ± 3.21 weeks, p = 0.035) neonates with a lower birth weight (1861.11 ± 869.9 vs. 3500 ± 424.26 g, p = 0.023) compared to women negative for the same allele. CONCLUSIONS: Thyroid hormone levels and the D1-C785T polymorphism, alone or in combination, correlate with the severity of preeclampsia. The D1-C785T polymorphism influences the outcome of pregnancy in severe preeclampsia.


Assuntos
Iodeto Peroxidase/genética , Pré-Eclâmpsia/sangue , Tiroxina/sangue , Tri-Iodotironina/sangue , Adulto , Feminino , Humanos , Polimorfismo de Nucleotídeo Único , Pré-Eclâmpsia/genética , Gravidez , Resultado da Gravidez , Romênia , Testes de Função Tireóidea , Adulto Jovem
3.
Eur Addict Res ; 4(4): 144-9, 1998 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-9852366

RESUMO

Alcohol Use Disorder and Associated Disabilities Interview Schedule - Alcohol/Drug-Revised (AUDADIS-A/D-R) is a fully structured, standardized and precoded instrument designed to evaluate alcohol and drug use disorders according to DSM-III-R, DSM-IV, and ICD-10 criteria. The AUDADIS-A/D-R has shown good to excellent reliability in both large clinical and general population samples, but prior to the conduct of the present study no data on the reliability of the Romanian version of the AUDADIS-A/D-R existed. The purpose of the present study was to examine the test-retest reliability of the alcohol module of the AUDADIS-A/D-R in a general population and clinical sample in Romania. The overall reliability of ICD-10 and DSM-IV abuse, harmful and dependence diagnoses, was found to be good to excellent, but was somewhat lower for abuse and harmful use diagnoses. The results are discussed in terms of the cultural applicability of the symptom items and within the context of the analysis of discrepant responses between the test and retest interviews.


Assuntos
Alcoolismo/diagnóstico , Pessoas com Deficiência , Entrevista Psicológica , Transtornos Relacionados ao Uso de Substâncias/diagnóstico , Organização Mundial da Saúde , Adulto , Feminino , Humanos , Masculino , Escalas de Graduação Psiquiátrica , Reprodutibilidade dos Testes , Romênia
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