RESUMO
We present a case of a 39-year-old man who presented with chronic bilateral upper extremity pain associated with innumerable angiomyolipomas that developed 5 years after a motor vehicle accident involving his upper extremities. Our case notes the rare nature of painful adipose tissue deposits and the diagnostic challenges.
Assuntos
Acidentes de Trânsito , Adipose Dolorosa/etiologia , Tecido Adiposo , Adipose Dolorosa/tratamento farmacológico , Adipose Dolorosa/fisiopatologia , Adulto , Amitriptilina/uso terapêutico , Analgésicos não Narcóticos/uso terapêutico , Angiomiolipoma/etiologia , Angiomiolipoma/fisiopatologia , Angiomiolipoma/cirurgia , Baclofeno/uso terapêutico , Dor Crônica/tratamento farmacológico , Dor Crônica/etiologia , Dor Crônica/fisiopatologia , Clonidina/análogos & derivados , Clonidina/uso terapêutico , Diagnóstico Diferencial , Humanos , Ibuprofeno/uso terapêutico , Masculino , Relaxantes Musculares Centrais/uso terapêutico , Tomografia Computadorizada por Raios X , Extremidade Superior/fisiopatologia , Extremidade Superior/cirurgiaRESUMO
Compression or irritation of the sciatic nerve and its branches, the common fibular and tibial nerves, causes sciatica which is a common syndrome characterized most often by radiating pain from the lower back down the legs and also manifesting as sensory and motor deficits. Sciatica is a common presentation of lumbosacral disc prolapse and degenerative disease of the lumbar spine in ambulatory settings. Schwannomas rarely cause sciatica; hence, it is seldom considered in evaluation of a patient with radiculopathy. Our patient presented with lumbar radiculopathy, mild degenerative changes on lumbar magnetic resonance imaging (MRI) scan, and failed conservative treatment. Myelopathy was confirmed with electromyogram (EMG). Thoracolumbar spine MRI revealed the schwannoma in the thoracic region. He recovered neurologic function after tumor excision. This case highlights the diagnostic challenge that may arise in evaluating a patient with lumbar radiculopathy, negative lumbosacral spine imaging, and failure of conservative therapy.
RESUMO
BACKGROUND: Patients with chronic pain often experience co-occurring depression and in some cases suicidal ideation. It is critical to discover risk factors for suicide in this vulnerable patient population. OBJECTIVE: To assess the prevalence of suicidal ideation and identify potential risk factors in patients with chronic non-cancer pain. STUDY DESIGN: Retrospective chart review. SETTING: Four hundred and sixty-six patients with chronic non-cancer pain referred to a behaviorally based pain program in a community health system. METHODS: Data collected included pain intensity and level of pain interference (Brief Pain Inventory), pain duration, pain site, depression level (Beck Depression Inventory Fast Screen for Medical Patients), anxiety (Beck Anxiety Inventory), personal and family psychiatric and substance use disorder history, level of isolation, and demographic data. Univariate and logistic regression analyses were performed. RESULTS: Results showed a high rate of suicidal ideation in this patient population (28%). Univariate analyses stratified by level of suicide (no suicidal ideation or passive/active suicidal ideation) revealed statistically significant group differences on pain location (extremity P = 0.046, generalized P = 0.047), work disruption (P = 0.049), social withdrawal (P < 0.001), pre-pain history of depression (P < 0.001), family history of depression (P < 0.001), and history of sexual/physical abuse (P < 0.001). Logistic regression revealed that history of sexual/physical abuse (Beta = 0.825; P = 0.020; OR = 2.657 [95% CI = 1.447 - 4.877]), family history of depression (Beta = 0.471; P = 0.006; OR = 1.985 [95% CI = 1.234 - 3.070]), and being socially withdrawn (Beta = 0.482; P < 0.001; OR = 2.226 [95% CI = 1.431 - 3.505]) were predictive of suicidal ideation. LIMITATIONS: Measure of depression was not included in data analysis to reduce effect of co-linearity. Also the study population was a specialty pain clinic allowing for possible subject selection bias. CONCLUSIONS: Results of this study are consistent with the prevailing literature on pain and suicide demonstrating a high prevalence of suicidal ideation in the chronic pain population. Novel predictive variables were also identified that will provide the basis for developing a risk stratification model that can be further tested prospectively in chronic pain patients.