Susceptibility Status of a Recently Introduced Population of Aedes albopictus to Insecticides Used by the Vector Control Program in Merida, Yucatan, Mexico.

In recent years, Aedes albopictus has become the most important invasive mosquito species worldwide. In 2018, Ae. albopictus was found in a suburban area of Merida, one of the cities with the highest number of arbovirus cases in Mexico in the last 10 years. As Ae. albopictus continues its range expansion, there is a need to monitor its susceptibility to existing insecticide classes, since countries like Mexico currently do not consider Ae. albopictus in its insecticide management programs. In order to determine its susceptibility to the insecticides usually applied by the vector control program in Mexico, the Centers for Disease Control and Prevention bottle bioassays were performed on individuals from established population of Ae. albopictus from Merida, Yucatan, Mexico. Results suggested that the population recently found in the suburban area of Merida is susceptible to permethrin, deltamethrin, chlorpyrifos, malathion, bendiocarb, and propoxur. Further studies of insecticide resistance using biochemical and molecular tools together with more knowledge of the biology and ecology of this species are necessary to generate specific and efficient control strategies in Mexico.

Bio-Efficacy of Commercially Available Residual Insecticides for the Control of Aedes aegypti in Mexico.

Commercial aerosolized insecticides can be implemented as a community-based approach to targeted indoor residual spraying against Aedes aegypti, but their efficacy on pyrethroid-resistant mosquitoes has not yet been evaluated. Two commercial aerosolized products (H24 Poder Fulminante Ultra Eficaz®, carbamate, and Baygon Ultra Verde®, pyrethroid) were sprayed on common indoor surfaces e.g., cement, plywood, and cloth, and tested for their residual efficacy on susceptible and field-derived pyrethroid-resistant Ae. aegypti strains using the WHO cone bioassays. Overall, ≥80% 24-h mortality was observed for both products for at least 4 wk regardless of the mosquito strain or surface type used. H24 Poder Fulminante Ultra Eficaz showed the highest residual potency, sustaining >80% mortality for 7-wk posttreatment regardless of mosquito strain and surface type. For Baygon Ultra Verde, the mean mortality of female Ae. aegypti remained >80% for a shorter period (4-6 wk). Nonpyrethroid commercial aerosolized formulations can provide a lasting residual effect indoors compatible with the need for rapid and lasting mosquito control during outbreaks and may be suitable for community-based targeted indoor residual spraying.

Efficiency signal conversion parameter to evaluate astigmatic femtosecond-optical parametric oscillator cavities.

In this work, we define the efficiency signal conversion numerical parameter, Veff, useful to evaluate the operation efficiency of femtosecond-Optical Parametric Oscillator (fs-OPO) cavities considering the astigmatism effect. For the validation of the Veff, we have performed experimental measurements. We present different high efficiency home-made singly resonant fs-OPO cavities, with signal tuneability from 1.1 µm to 1.6 µm based on a 0.5 mm Periodically Poled Lithium Niobate doped with MgO (MgO:PPLN) crystal. We have also defined the pump energy threshold per crystal unit length, ζp,th. Pump threshold, achieved by following the Veff, was 142 mW at 810 nm, and ζp,th = 2.10 nJ/mm, the lowest value, in comparison with other studies. The Veff is based on an ABCD matrix Gaussian beam propagation method, which calculates the mode coupling between the pump and signal beams along the crystal under different cavity configurations taking into account the astigmatism. The model was compared and tested with 3 different experimental singly resonant fs-OPO ring cavity configurations that we have defined as single-folded, two-folded, and direct-pump cavity.

[Cardiopulmonary dynamics during a maximal exertion test in Mexican endurance athletes]. / Dinámica cardiopulmonar durante una prueba de esfuerzo máximo en atletas mexicanos de resistencia.

AIM: To search for cardiopulmonary (CP) kinetic and dynamic differences between Mexican resistance athletes (RES = 10) and non athletes (NON = 19). METHOD: From the expired volume (Ve), measured by an open circuit spirometry, we calculated both VO2 and VCO2 during stress test while the volunteer pedalled seated on an electronic cycloergometer that started at 50 W.2 min-1 followed by increments of 25 W.2 min-1 each, until VO2máx was reached. The exercise transient time course (min) response (VO2, VCO2, Ve and heart rate, HR; and also O2 pulse, PulO2) was transformed to seconds and modelled by computer using linear regression technique by the interactive minimum squares method, and the mean response time (MRT) was used as an overall kinetic CP parameter. RESULTS: The transient MRTs for VO2, VCO2 and Ve were slow in RES compared to NON. While the transient CP dynamics in NON lasted MRT_VO2 < (MRT_PulO2, MRT_FC) < MRT_VCO2 < MRT_Ve; the RES: both MRT_PulO2 and MRT_HR shifted to the right ((MRT_VO2, MRT_VCO2) < (MRT_PulO2, MRT_FC) < MRT_Ve). The relationships between the best sport profit mean velocity and both the MRT_VO2, MRT_VCO2 and MRT_PulO2 (GEK = gas exchange kinetics) showed fast_RES and slow_GEK, and slow_RES and fast_GEK. CONCLUSION: The transient CP kinetics was slow in RES compared NON. It is possible to distinguish cardiopulmonary kinetic differences among resistance athletes holding different sport profiles.

Treatment of presumed bacterial pneumonia in ambulatory children.

In a prospective, randomized, open study, a combination of trimethoprim and rifampin (TMP/R) 20 mg/kg/day was compared with ampicillin (AMP) 150 mg/kg/day, both given orally twice daily for 10 days, for the treatment of 60 children who had mild community-acquired pneumonia. The control group comprised 112 healthy children. The overall duration of the disease was 8.5 +/- 3.6 days in the TMP/R group vs 6.0 +/- 1.1 days in the AMP group. Fever persisted for 7.0 +/- 1.8 days in the TMP/R-treated patients vs 5.2 +/- 1.0 days in the AMP-treated patients. At the end of the 10 days, nasopharyngeal cultures were negative in all patients in the AMP group and in 25 of the 30 patients in the TMP/R group. These five patients were clinical and microbiologic failures. We conclude that in infants and children with mild community-acquired pneumonia, treatment with AMP for 10 days is more effective than treatment with a combination of TMP/R for clinical cure and eradication of bacterial pathogens.

[The control of urban growth in Mexico City. Suppositions regarding poor planning]. / El control de la expansion urbana en la ciudad de Mexico. Conjeturas de un falso planteamiento.

PIP: It is argued that mechanisms for planning land use and controlling urban expansion in Mexico City have failed to achieve their aims. Although in theory Mexico's urban planning process has recently attempted to go beyond purely physical aspects to include socioeconomic dimensions, it has in fact been inflexible and oriented to exclusively to technical and administrative aspects, to the detriment of social distribution goals. Planning instruments have not included important aspects such as specific mechanisms for altering employment structures or income levels or mechanisms for providing access to land or housing to the most disadvantaged groups. The urban planning process in Mexico City, instead of assuming a socially compensatory role in favor of disadvantaged groups, has maintained the status quo or discriminated in favor of the already advantaged. The spatial and technical orientation or urban planning in Mexico City does not leave room for a well-defined social policy. The population of the Mexico City metropolitan Zone increased from 3 million in 1950 to 18 million in 1985, while its total area increased from 11,750 hectares in 1940 to 125,000 in 1985. Transfer of population from the Federal District to the conurban municipios of the state of Mexico has been very significant since the 1970s. Around 20% of the total area of metropolitan Mexico City has been settled through illegal means, with communal and ejido lands accounting for a large share. Settlements on some 60% of lands in metroplitan Mexico City were illegal or irregular at some time. Low income housing is the cheapest form for the government because the frequently illegal status of settlers prevents them from making any demands for services or equipment for the 1st several years. Construction is undertaken and financed almost entirely by the settlers themselves, freeing the government of responsibility in regard to the constitutionally mandated right of all Mexicans to housing. The Urban Development Plan of the state of Mexico published in 1986 proposed 2 important programs for controlling urban growth. The territorial reserves program aimed to anticipate the need and make available through purchase, expropriation, or other means sufficient lands for housing to which the lowest income groups would share access. The "Paint Your Line" program establiished physical limits for urban expansion in each of the 17 conurban municipios in the State of Mexico. To date, however, few lands have been set aside for legal acquisition and the Paint Your Line program has been slow in delimiting the areas to be settled. Data from a 1989 study in the municipios of Chalco and Ixtapaluca demonstrate the shortcomings of the programs, which do not address the true processes and agents that control new settlements and especially illegal occupations and which fail to satisfy the needs of low-income population sectors.^ieng