[The mobile applications developed for self-control arterial pressure: systematic review and content-analysis].

The high prevalence of arterial hypertension and necessity for permanent monitoring of blood pressure requires implementation of new methods of interaction between patient and physician in order to optimize medical care. The purpose of the study was to describe and to evaluate functional possibilities of Russian-speaking mobile applications utilized in collecting blood pressure readings to monitor efficiency of arterial hypertension treatment. The study was carried out in June 2023 in three mobile application stores: Apple Store, Google Play and RuStore. The Russian-speaking applications applied to hypertension self-controlling were considered. For final analysis 45 mobile applications were selected out of 380 applications tested. The most common functions, besides fixing blood pressure levels, were ability of fixing pulse rate (n=41), weight (n=21), sugar level (n=10), blood oxygen saturation (n=8), cholesterol (n=6), rhythm disturbances (n=6) and body temperature (n=5). Additionally, applications made it possible to add tags (n=33), to view statistics (n=41) (including average blood pressure (n=8), pulse pressure (n=9), average daily blood pressure (n=6) and to compare data for different periods of time (n=6), to filter data by tags (n=17), to export statistics (n=32). The 6 applications also supported technology of wireless reception of blood pressure and emergency data. The educational information about blood pressure was enclosed in 17 applications and dietary advice in 12 applications. The content included basic information about blood pressure, treatment, diet, and physical activity. No clinical studies that proved efficiency or inefficiency of analyzed applications were found. None of descriptions comprised both involvement of physicians in development of application and use of clinical recommendations. The results demonstrated large choice of applications used in recording blood pressure with purpose of hypertension self-control. Besides, mobile applications contain various functions and their combinations that can help patient to control blood pressure more effectively. The physicians are to be aware of capabilities of mobile applications developed with purpose of monitoring health of patients.

COMPARATIVE ANALYSIS OF THE EFFECTS OF SOME HEPATOPROTECTORS IN EXPERIMENTALLY INDUCED MAFLD IN ADULT WISTAR RATS.

Metabolic associated fatty liver disease (MAFLD) is one of the most common chronic diseases characterized by increased fat accumulation in the liver and metabolic dysfunction. MAFLD is now taking on the character of a pandemic. In addition to dietary therapy and physical activity, hepatoprotectors are included in the pharmacotherapy of MAFLD. This study was to perform a comparative analysis of the efficacy of some hepatoprotectors in experimentally induced MAFLD in adult Wistar rats.

[Omentoplasty of residual cavities of the liver]. / Omentoplastika ostatochnykh polostei pecheni.

Results of omentoplasty of residual cavities of the liver are described. New variants of operations of omentoplasty following hydatidectomy and abscessotomy gave good near and remote results of the treatment.

[Diagnosis and treatment of missed abortion]. / Diagnostika i lechenie nesostoiavshegosia vykidysha.

PIP: Literature on the etiology, diagnosis, and treatment of missed abortion is reviewed. Missed abortion during the 1st 28 weeks of gestation is defined as retention in the uterus of an abortus. The incidence of missed abortion among spontaneous miscarriages is 2.6-9.4%. Etiology of missed abortion is associated with intrauterine infections, severe abnormalities, inhibition of uterine contraction, or impairment of the hormonal balance. Prolonged retention of an abortus can result in fetal maceration or mummification. Clinical manifestations of missed abortion include absence of fetal heart tone, discharge from the breasts and diminution of their size, general fatigue, fever, and sometimes skin itch. Diagnosis of missed abortion is based upon the results of general and gynecologic examinations. Missed abortion is characterized by cessation of growth of the uterus, decrease in cyanosis of the cervix uteri, decrease in urinary excretion of estriol (up to 0-5 mg/day), drastic decrease in excretion of chorionic gonadotropin, decrease in blood level of placental lactogen, and decrease in pregnadiol excretion. Echographic signs of missed abortion during the 1st trimester include absence of heart activity, absence of fetal movements, and changes in the size of the uterus, amniotic cavity, and embryo. The most frequent complications of missed abortion are uterine hemorrhage, infection, and malignant transformation. Treatment of women with missed abortion consists of administration of abortifacient agents and curettage. The most frequently used abortifacient agents are oxytocin in large dosages, intravenous infusions of prostaglandin e2 (PGE2) or single intraamniotic injection of 15-methyl-PGF2alpha. The women with threatening uterine hemmorrage can be subjected to hysterectomy.^ieng