[Plasma lipid spectrum in acute leukemia]. / Osobennosti lipidnogo spektra plazmy pri ostrykh leikozakh.

The examination of 54 patients with acute leukemia (AL) found out ambiguous changes in plasmic lipid spectrum typical for elderly patients. Hypocholesterolemia occurred more frequently in nonlymphoblastic AL, is accompanied with severe anemia and infectious-septic complications. Hyperlipidemia was more common among senile AL patients with coronary heart disease which contributed to circulatory failure, cardiac arrhythmia, pneumonia complications and eventually to shorter survival of AL patients.

[Ultrasonographic characteristics of the liver in chronic and acute leukemia]. / Ul'trazvukovaia kharakteristika pecheni pri ostrykh i khronicheskikh leikozakh.

Parenchyma of the liver and blood flow in the portal system were studied in patients with acute and chronic leukemias. Ultrasonic investigations of the liver with the use of Doppler's method were conducted in 82 leukemia patients. It has been found that in most cases of leukemia not only the size but also ultrasonic characteristics of parenchyma of the liver are changed. The echo-structure of the liver depends, first of all, on the duration of the disease and chemotherapy conducted, and, to a lesser degree, on the clinico-morphological forms of leukemias. At the same time a rise is observed in the portal blood flow rate that may be compensatory in response to anemia. Pronounced dilatation of the splenic vein and of the main stem of the hepatic vein, as well as an increased minute blood volume in hepatic vein of chronic leukemia patients, are, probably, caused by increased venous outflow from the enlarged spleen.

[Characteristics of the clinical course of acute drug-induced agranulocytosis (data of the Hematological Department for the 6-year period--1982-1987)]. / Osobennosti klinicheskogo techeniia ostrogo medikamentoznogo agranulotsitoza (po materialam gematologicheskogo otdeleniia za 6 let--1982-1987 gg.).

The clinical characteristics of agranulocytosis in its varying forms have been presented that determine the therapeutic tactics at different stages of the disease. It has been stressed that the prevention and treatment of infectious complications, control of intoxication should be considered as the most important measures. Glucocorticoid hormones present only a symptom complex of the antishock therapy.