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1.
Artigo em Alemão | MEDLINE | ID: mdl-38811445

RESUMO

Drug reaction with eosinophilia and systemic symptoms (DRESS) is an illness which is difficult to diagnose because of its various symptoms. In our case, a patient with small spotted exanthema with nearly erythroderma and eosinophilia presented to the emergency room. Systemic steroid therapy was started on suspicion of a drug reaction. Over the course of time, the patient's general condition deteriorated significantly and the patient developed cholecystitis, Staphylococcus aureus bacteremia, pneumonitis and cytomegalovirus reactivation. With this case report, we want to show that DRESS is a disease that is difficult to treat and can develop after a long delay.

2.
Hautarzt ; 71(3): 223-226, 2020 Mar.
Artigo em Alemão | MEDLINE | ID: mdl-31950210

RESUMO

Pemphigoid gestationis (PG) is a blistering autoimmune skin disease, typically occurring in the second and third trimester of pregnancy. Aberrant expression of major histocompatibility complex (MHC) class II molecules on the chorionic villi seems to lead to antibody production against bullous pemphigoid (BP)-180. We report a case of PG in a woman whose pregnancy was achieved using egg donation. Since the entire fetal genome is allogeneic to the mother, augmented immune reaction in egg-donated pregnancies appears to trigger the occurrence of PG.


Assuntos
Doenças Autoimunes , Vesícula/complicações , Penfigoide Gestacional/patologia , Dermatopatias Vesiculobolhosas/complicações , Adulto , Vesícula/patologia , Feminino , Humanos , Penfigoide Gestacional/imunologia , Penfigoide Bolhoso/imunologia , Gravidez , Resultado da Gravidez , Dermatopatias Vesiculobolhosas/patologia , Urticária/patologia
3.
Hautarzt ; 70(7): 530-534, 2019 Jul.
Artigo em Alemão | MEDLINE | ID: mdl-30937478

RESUMO

Adult-onset Still's disease (AOSD) is a rare systemic inflammatory disease characterized by high spiking fever, arthritis, salmon-pink maculopapular rash and multiple organ involvement. We report a case of an adult-onset Still's disease that meets Yamaguchi's criteria and presented with typical clinical manifestations. AOSD is treated with anti-inflammatory medications. Standard therapy includes corticosteroids. Other medications like azathioprine, methotrexate or interleukin-1 or -6 blockers can be used when standard steroid treatment is not adequate.


Assuntos
Corticosteroides/uso terapêutico , Exantema/patologia , Doença de Still de Início Tardio/diagnóstico , Adulto , Idade de Início , Anti-Inflamatórios/uso terapêutico , Artrite/etiologia , Exantema/etiologia , Febre/etiologia , Humanos , Doença de Still de Início Tardio/tratamento farmacológico , Doença de Still de Início Tardio/imunologia , Síndrome
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