RESUMO
Varicella-associated purpura fulminans is a rare syndrome associated with substantial morbidity and mortality. General supportive care, heparinization, and plasma infusions are the mainstays of treatment. A patient aged 8 years and 8 months with purpura fulminans and multiple deep vein thromboses after varicella infection because of deficiencies of proteins C and S is presented in this case report.
Assuntos
Varicela/complicações , Deficiência de Proteína C/complicações , Deficiência de Proteína S/complicações , Púrpura Fulminante/etiologia , Trombose Venosa/etiologia , Anticoagulantes/uso terapêutico , Testes de Coagulação Sanguínea , Transfusão de Componentes Sanguíneos , Criança , Glucocorticoides/uso terapêutico , Heparina/uso terapêutico , Humanos , Masculino , Metilprednisolona/uso terapêutico , Nadroparina/uso terapêutico , Deficiência de Proteína C/diagnóstico , Deficiência de Proteína C/terapia , Deficiência de Proteína S/diagnóstico , Deficiência de Proteína S/terapia , Púrpura Fulminante/patologia , Púrpura Fulminante/terapia , Púrpura Fulminante/virologia , Resultado do Tratamento , Ultrassonografia Doppler , Trombose Venosa/diagnóstico por imagem , Trombose Venosa/terapia , Trombose Venosa/virologiaRESUMO
INTRODUCTION: We evaluated chest X-ray and clinical findings of patients with lower respiratory tract infection due to influenza H5N1 and presented the radiological findings and clinical course of the infection. MATERIALS AND METHODS: Between December 2005 and February 2006, eight hospitalized patients (median age 10, 5-15 years) with avian-flu were evaluated in this study. All patients were evaluated with chest X-ray and four of them with CT scan. Post mortem pathological characterization were also available for three of the patients. RESULTS: A rapidly progressive pneumonia with high mortality rate was observed especially for cases with late admission. The major radiologic abnormalities were extensive pneumonic infiltration with segmental and multifocal distribution, mostly located in lower zones of the lung. No pleural effusion and hilar lymphadenopathy was noted. CONCLUSION: Avian flu may be presented as rapidly progressive pneumonia. The chest radiography has an important role in diagnosis and should be obtained daily because of rapid change of the findings that may necessitate prompt action.
