RESUMO
Nodular cutaneous amyloidosis is a rare disease that predominantly affects women in their sixth and seventh decades. The genital organ is the rarest cutaneous location with only four reported cases of vulvar involvement. We report the first known case of this entity involving the glan penis. The clinical feature of nodular cutaneous amylodosis, the histopathology, the pathogenesis and the therapy are discussed.
Assuntos
Amiloidose/diagnóstico , Doenças do Pênis/diagnóstico , Dermatopatias/diagnóstico , Amiloidose/patologia , Amiloidose/cirurgia , Diagnóstico Diferencial , Humanos , Masculino , Microscopia Eletrônica , Pessoa de Meia-Idade , Doenças do Pênis/patologia , Doenças do Pênis/cirurgia , Dermatopatias/patologia , Dermatopatias/cirurgiaRESUMO
Contact dermatitis from lacquer has been documented. The causative agent is a resin from a lacquer tree that can induce either irritation or sensitization. Thai and Japanese lacquer trees are 2 distinct species but are both members of the Anacardiaceae family. We report 3 cases of contact dermatitis from Thai lacquer resin. Observation and study of the lacquer plantation and working process at the factory were made to elucidate the aetiology of the dermatitis.
Assuntos
Dermatite Alérgica de Contato/etiologia , Dermatite Ocupacional/etiologia , Laca/efeitos adversos , Resinas Vegetais/efeitos adversos , Adolescente , Adulto , Estudos de Casos e Controles , Dermatite Alérgica de Contato/diagnóstico , Dermatite Alérgica de Contato/epidemiologia , Dermatite Irritante/etiologia , Dermatite Ocupacional/diagnóstico , Dermatite Ocupacional/epidemiologia , Feminino , Humanos , Masculino , Testes do Emplastro/métodos , Tailândia/epidemiologiaRESUMO
Allergic contact cheilitis describes a not uncommon inflammatory reaction of the lips. We reviewed its allergic causes, and suspect that the literature does not adequately document the frequency and etiologic factors involved.
Assuntos
Queilite/induzido quimicamente , Dermatite Alérgica de Contato/etiologia , Queilite/imunologia , Cosméticos/efeitos adversos , Materiais Dentários/efeitos adversos , Hipersensibilidade a Drogas/etiologia , Hipersensibilidade Alimentar/etiologia , Humanos , Lábio/anatomia & histologia , Lábio/patologiaRESUMO
In spite of not knowing the numbers of people exposed and obviously incomplete reporting, the known mechanisms of alcohol cutaneous intolerance and the literature classified according to mechanisms are listed. Testing techniques for delayed- and immediate-types are proposed.
Assuntos
Álcoois/efeitos adversos , Dermatite Alérgica de Contato/etiologia , Urticária/induzido quimicamente , Aldeídos/efeitos adversos , Dermatite Alérgica de Contato/imunologia , Etanol/efeitos adversos , Humanos , Síndrome , Urticária/imunologiaAssuntos
Anti-Inflamatórios não Esteroides/efeitos adversos , Dermatite Alérgica de Contato/etiologia , Dermatite Fotoalérgica/etiologia , Toxidermias/etiologia , Administração Tópica , Anti-Inflamatórios/efeitos adversos , Dermatite Alérgica de Contato/diagnóstico , Dermatite Alérgica de Contato/epidemiologia , Dermatite Fotoalérgica/diagnóstico , Dermatite Fotoalérgica/epidemiologia , Toxidermias/diagnóstico , Toxidermias/epidemiologia , HumanosRESUMO
Ninety-eight cases of various types of pemphigus were treated between 1978-1987. Sixty-one cases were pemphigus vulgaris (PV), 22 cases were pemphigus foliaceus, generalized type (PFG) in which one case developed pemphigus vegetans, 11 cases were pemphigus foliaceus localized type (PFL), and four cases were pemphigus erythematosus (PE). Fifteen mild cases of PV and three mild PFG were treated with corticosteroid (prednisolone or prednisone) alone, and dapsone or cyclophosphamide (CP) were added as treatment failed in two cases of each. Dapsone alone was used effectively in three cases of mild PV. Eight cases of moderate and three cases of severe PV, as well as five cases of moderate PFG, failed to respond to corticosteroid alone but were cleared by the addition of CP. Thirty-two moderate cases of PV and PFG treated with a combination of corticosteroid 60 mg/day plus initial CP and 14 severe cases of PV and PFG treated with corticosteroid 120 mg/day plus initial CP, resulted in clearing skin lesions in 2 months. Azathioprine or chlorambucil were substituted in three cases who developed CP toxicity. Addition of gold sodiumthiomalate in six refractory cases when the above regimens failed, caused a complete remission in two and partial control in four. Higher dosage of prednisolone or prednisone more than 120 mg/day has never been used. Eleven cases of PFL and four cases of PE were treated with uneventfully good results. Intercellular antibody titers became negative within 4.67 months except in refractory cases, however, the treatment was continued for at least 3 years. Herpes simplex superimposed infection was more common than herpes zoster infection.(ABSTRACT TRUNCATED AT 250 WORDS)
