RESUMO
BACKGROUND: Considering consumer trends toward the use of "clean" personal care products and increasing recognition of childhood allergic contact dermatitis, we sought to characterize the allergen profile of such children's products. METHODS: Ingredients of baby washes/shampoos, bubble baths, and moisturizers identified using the "Clean Baby" filter on Target®'s online marketplace were analyzed for relevant pediatric contact allergens. RESULTS: Product compositions declared fragrance in 82% of products, Compositae in 46%, cocamidopropyl betaine in 45%, glucosides in 37%, propylene glycol in 12%, lanolin in 1%, and no allergens in 9%-methylisothiazolinone and formaldehyde were not found. CONCLUSION: Children are greatly impacted by atopic dermatitis and skin barrier dysfunction, which underscores a need for greater public awareness of sensitizing and irritating ingredients, particularly regarding pediatric personal care products.
Assuntos
Alérgenos , Dermatite Alérgica de Contato , Humanos , Alérgenos/efeitos adversos , Alérgenos/análise , Dermatite Alérgica de Contato/etiologia , Criança , Cosméticos/efeitos adversos , Cosméticos/química , Qualidade de Produtos para o Consumidor , Propilenoglicol/efeitos adversos , Propilenoglicol/análiseRESUMO
We present a case of cutaneous granulomatous disease associated with rubella virus in a 4-year-old girl without an identifiable immunodeficiency. In this case, a combination of anti-inflammatory, anti-viral, and anti-neutrophil therapies successfully treated vision-threatening eyelid, conjunctival, scleral, and orbital inflammation.
Assuntos
Síndromes de Imunodeficiência , Dermatopatias , Feminino , Humanos , Pré-Escolar , Vírus da Rubéola , Granuloma/tratamento farmacológico , Dermatopatias/complicações , Pálpebras , Inflamação/complicaçõesAssuntos
Vesícula/etiologia , Mastocitose Cutânea/diagnóstico , Humanos , Lactente , Masculino , Triptases/sangueAssuntos
Anticorpos Monoclonais Humanizados/efeitos adversos , Dermatite Atópica/tratamento farmacológico , Pancreatite/induzido quimicamente , Adolescente , Antibacterianos/uso terapêutico , Ciclosporina/uso terapêutico , Fármacos Dermatológicos/uso terapêutico , Doxiciclina/uso terapêutico , Glucocorticoides/uso terapêutico , Humanos , Masculino , Prednisona/uso terapêuticoRESUMO
Patch testing is the gold-standard diagnostic tool for the diagnosis of allergic contact dermatitis; unfortunately, it is a procedure with potential for errors, including false-negative reactions. Some of the factors responsible for this are likely unavoidable; however, others may potentially lie within the control of the user. Knowledge and management of these controllable factors may improve the outcome of patch testing and minimize the incidence of false-negative patch test results.
