Contributions of Demand/Withdraw Processes and Alcohol Consumption on Emotional Flooding in Distressed Violent versus Distressed Non-Violent Couples.

Purpose: Although alcohol-related intimate partner violence (IPV) is a serious public health problem, the mechanisms underlying this association are poorly understood. For instance, prior research has shown differences in distressed violent (DV) and distressed nonviolent (DNV) couples' demand/withdraw communication and the extent to which they become emotionally flooded (i.e., physiologically aroused) in response to conflict. Additionally, alcohol use is associated with increased demand/withdraw communication, IPV, and emotional flooding. Therefore, the present study sought to clarify the association between demand/withdraw communication and emotional flooding among relationally couples who use alcohol and who do and do not experience IPV. Methods: Relationally distressed couples (Mage =30.1 years) reported on their physical aggression, demand/withdraw communication, emotional flooding, and total number of drinks during the past six months. Couples were denoted as DV (N = 58) if at least one partner reported IPV and DNV (N = 29) if neither partner reported IPV. Actor-partner interdependence modeling was used to test whether couple type (DV versus DNV) moderates the link between demand/withdraw behavior and emotional flooding. Results: With one exception, alcohol use was unrelated to any of the processes under investigation in the current study. Moreover, men's and women's report of a woman-demand/man-withdraw pattern and man-demand/woman-withdraw pattern, respectively, were positively associated with each partner's own emotional flooding. Couple type (DV vs DNV) did not moderate these associations. Conclusions: The present results highlight the need for sensitive measures that can capture the nuanced processes that underlie IPV in couples who use alcohol.

Online support for all: Examining participant characteristics, engagement, and perceived benefits of an online harm reduction, abstinence, and moderation focused support group for alcohol and other drugs.

OBJECTIVE: Online support groups for individuals with substance use disorders are regularly used, yet little is known about participant engagement patterns. Preliminary research has examined utilization and perceived benefits of an abstinence-focused online social network. This study sought to extend these findings by examining participant characteristics, engagement, and perceived benefits of online support groups for individuals with broader personal substance use goals (Harm reduction, Abstinence, and Moderation Support [HAMS]). METHOD: HAMS members were invited to complete an online survey about their HAMS engagement (N = 343). The average age of participants was 41.55 (SD = 12.61) and most identified as White (93.9%), female (78.8%), and cisgender women (70.1%). Participants completed measures of HAMS participation, substance use goal, quantity/frequency of substance use, mental health history, negative substance use-related consequences, and quality of life. RESULTS: Most participants (67.1%) reported a substance use moderation goal and alcohol was the most commonly used substance (91.6%). Participants most frequently reported visiting HAMS on Facebook (89.5%), visiting HAMS daily (39.2%), and visits typically lasted up to 30 min (86.1%). Most participants somewhat or strongly agreed HAMS helped them feel better about changing their use of drugs/alcohol (87.1%; M = 4.41/5; SD = 0.81), increased their motivation for changing their use of drugs/alcohol (89.2%; M = 4.44/5; SD = 0.77), and increased their self-efficacy in reaching/maintaining the substance use goals (85.1%; M = 4.29/5; SD = 1.05). CONCLUSIONS: Online support for broader personal substance use goals may be beneficial for individuals who seek to stop/limit their substance use. Online support is well suited for obtaining quick, inexpensive access to support. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Cinema:Bandit: a visualization application for beamline science demonstrated on XFEL shock physics experiments.

A new visualization tool, Cinema:Bandit, and its demonstration with a continuous workflow for analyzing shock physics experiments and visually exploring the data in real time at X-ray light sources is presented. Cinema:Bandit is an open-source, web-based visualization application in which the experimenter may explore an aggregated dataset to inform real-time beamline decisions and enable post hoc data analysis. The tool integrates with experimental workflows that process raw detector data into a simple database format, and it allows visualization of disparate data types, including experimental parameters, line graphs, and images. Use of parallel coordinates accommodates the irregular sampling of experimental parameters and allows for display and filtering of both experimental inputs and measurements. The tool is demonstrated on a dataset of shock-compressed titanium collected at the Matter in Extreme Conditions hutch at the Linac Coherent Light Source.

Bento Box: An Interactive and Zoomable Small Multiples Technique for Visualizing 4D Simulation Ensembles in Virtual Reality.

We present Bento Box, a virtual reality data visualization technique and bimanual 3D user interface for exploratory analysis of 4D data ensembles. Bento Box helps scientists and engineers make detailed comparative judgments about multiple time-varying data instances that make up a data ensemble (e.g., a group of 10 parameterized simulation runs). The approach is to present an organized set of complementary volume visualizations juxtaposed in a grid arrangement, where each column visualizes a single data instance and each row provides a new view of the volume from a different perspective and/or scale. A novel bimanual interface enables users to select a sub-volume of interest to create a new row on-the-fly, scrub through time, and quickly navigate through the resulting virtual "bento box." The technique is evaluated through a real-world case study, supporting a team of medical device engineers and computational scientists using in-silico testing (supercomputer simulations) to redesign cardiac leads. The engineers confirmed hypotheses and developed new insights using a Bento Box visualization. An evaluation of the technical performance demonstrates that the proposed combination of data sampling strategies and clipped volume rendering is successful in displaying a juxtaposed visualization of fluid-structure-interaction simulation data (39 GB of raw data) at interactive VR frame rates.

Drag and Track: A Direct Manipulation Interface for Contextualizing Data Instances within a Continuous Parameter Space.

We present a direct manipulation technique that allows material scientists to interactively highlight relevant parameterized simulation instances located in dimensionally reduced spaces, enabling a user-defined understanding of a continuous parameter space. Our goals are two-fold: first, to build a user-directed intuition of dimensionally reduced data, and second, to provide a mechanism for creatively exploring parameter relationships in parameterized simulation sets, called ensembles. We start by visualizing ensemble data instances in dimensionally reduced scatter plots. To understand these abstract views, we employ user-defined virtual data instances that, through direct manipulation, search an ensemble for similar instances. Users can create multiple of these direct manipulation queries to visually annotate the spaces with sets of highlighted ensemble data instances. User-defined goals are therefore translated into custom illustrations that are projected onto the dimensionally reduced spaces. Combined forward and inverse searches of the parameter space follow naturally allowing for continuous parameter space prediction and visual query comparison in the context of an ensemble. The potential for this visualization technique is confirmed via expert user feedback for a shock physics application and synthetic model analysis.

Atg23 and Atg27 act at the early stages of Atg9 trafficking in S. cerevisiae.

Atg9 is a conserved multipass transmembrane protein with an essential role in autophagy. In Saccharomyces cerevisiae, it travels through the secretory pathway to a unique compartment, the Atg9 peripheral structures. These structures are then targeted to the phagophore assembly site (PAS), where they are proposed to help deliver membrane to the forming autophagosome. We used 'in vivo reconstitution' of this process in a multiple-knockout strain to define four proteins, Atg11, Atg19, Atg23 and Atg27, as the core minimal machinery necessary and sufficient for the trafficking of Atg9 to the PAS. Atg23 and Atg27 function in the formation of the Atg9 peripheral structures. Overexpression of Atg9 can bypass the need for Atg23, suggesting that the amount of Atg9 in each peripheral structure is a critical factor in their targeting to the PAS. In contrast, overexpression of Atg23 or Atg27 interferes with Atg9 trafficking, suggesting that these proteins must be present in the appropriate stoichiometry in order to function properly. These data allow us to resolve existing controversies regarding the role of Atg23 and Atg27, and propose a model that ties together previous observations regarding the role of Atg9 in autophagosome formation.