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J Pediatr Hematol Oncol ; 43(2): e207-e211, 2021 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-32205783

RESUMO

Orthopedic surgeons are well aware of tumor contamination at the site of initial biopsy in osteosarcoma. However, tumor contamination in patients with osteosarcoma associated with thoracic instrumentation is not well described. The authors summarize 2 reported cases in addition to the 2 cases at their institution of this phenomenon. Knowledge of tumor contamination and preventative measures against tumor contamination is sparse in the literature, especially pertaining to patients with osteosarcoma undergoing thoracic instrumentation. In this report, the authors hope to increase awareness of these cases and suggest preventative measures to mitigate against tumor contamination in patients with osteosarcoma. The authors report that the median time between thoracic instrumentation and the visible detection of tumor migration to local sites was 5 months. They conclude that tumor contamination associated with thoracic instrumentation is characterized by patients with multiple sites of relapse and aggressive, fatal disease.


Assuntos
Neoplasias Ósseas/cirurgia , Neoplasias Encefálicas/secundário , Procedimentos Cirúrgicos Minimamente Invasivos/efeitos adversos , Osteossarcoma/cirurgia , Complicações Pós-Operatórias/diagnóstico , Neoplasias de Tecidos Moles/secundário , Vértebras Torácicas/cirurgia , Adolescente , Adulto , Neoplasias Ósseas/patologia , Neoplasias Encefálicas/etiologia , Humanos , Masculino , Osteossarcoma/patologia , Complicações Pós-Operatórias/etiologia , Prognóstico , Neoplasias de Tecidos Moles/etiologia , Vértebras Torácicas/patologia , Adulto Jovem
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