Assuntos
Cistite/tratamento farmacológico , Sulfadiazina/uso terapêutico , Trimetoprima/uso terapêutico , Infecções Urinárias/tratamento farmacológico , Infecções Bacterianas/tratamento farmacológico , Ensaios Clínicos como Assunto , Quimioterapia Combinada , Feminino , Humanos , Sulfadiazina/administração & dosagem , Trimetoprima/administração & dosagemAssuntos
Anti-Infecciosos Urinários/uso terapêutico , Cistite/tratamento farmacológico , Infecções Urinárias/tratamento farmacológico , Adulto , Idoso , Andinocilina Pivoxil/uso terapêutico , Infecções Bacterianas/tratamento farmacológico , Feminino , Humanos , Pessoa de Meia-Idade , Sulfadiazina/uso terapêutico , Sulfametoxazol/uso terapêutico , Trimetoprima/uso terapêuticoRESUMO
In haematuria blood clots may form in the renal pelvis, with risk of outflow obstruction, impairment of renal function, pain and infection. The clots can also provide a matrix for stone formation. Ureteral catheterization and/or pyelostomy may be required if clots are not spontaneously excreted. Based on experience from a case of intrapelvic clotting due to haematuria after renal biopsy, a technique of coagulolysis is described. Via a ureteral catheter a solution of serum and streptokinase was intermittently infused into the renal pelvis. The case is presented. The clots disintegrated within 48 hours and urinary excretion recommenced, with reversal of rise in the blood creatinine level. There were no complications from the procedure, which seems to be a satisfactory alternative to surgical evacuation of clot.
Assuntos
Coagulação Sanguínea/efeitos dos fármacos , Fibrinólise , Doença Iatrogênica/tratamento farmacológico , Pelve Renal , Estreptoquinase/uso terapêutico , Biópsia/efeitos adversos , Humanos , Masculino , Pessoa de Meia-Idade , Estreptoquinase/administração & dosagem , Ureter , Cateterismo UrinárioRESUMO
In order to examine the reported beneficial effects of hemodialysis in chronic schizophrenic patients, a double-blind crossover study was carried out. Of the 47 patients considered for treatment, 10 diagnosed as chronic schizophrenics according to the Feighner and DSM-III criteria were accepted to the study. Seven of these patients completed the full program, four of whom belonged to a large family with a high incidence of schizophrenia. All patients were on antipsychotic medication throughout the study. Psychopathological evaluations were performed regularly in a blind fashion using the Comprehensive Psychopathological Rating Scale (CPRS) and the Nurse Observation Scale for Inpatient Evaluation (NOSIE-30). Samples of blood, urine, cerebrospinal fluid, and dialysate were obtained for examination. Three patients improved during active dialysis and two patients improved during sham treatment. Improvement in the five patients took place during the first treatment period. This study failed to demonstrate a therapeutic effect of hemodialysis superior to the sham procedures.