[Is there a relationship between the assessment of coronary risk on the Framingham and Sheffield tables and the sixth report of the Joint National Committee? Relationship between tables of coronary risk]. / ¿Existe relación entre la valoración del riesgo coronario según las tablas de Framingham y Sheffield con la del sexto informe del Joint National Committee? Relación entre tablas de riesgo coronario.

OBJECTIVES: To find the distribution of coronary risk (CR) in the various groups of hypertense patients in the Joint National Committee (JNC VI), using both the Framingham and Sheffield tables, and to assess whether there is a relationship between the different scales used. DESIGN: Descriptive study. SETTING: Tortosa Oeste Health District, Tarragona. Spain. PARTICIPANTS: Rural population between 30 and 74 years old with Hypertension, but without any background of cardiovascular pathology. MAIN MEASUREMENTS: The variables studied corresponded to the Anderson table in the Framingham study, the Sheffield table and the JNC VI one. Concordance was assessed with the kappa coefficient. RESULTS: 148 hypertense patients with an average age of 62, 63.5% of whom were women, were studied. 23% had high CR on the Framingham, and 42.1% on the Sheffield. Distribution of the sample according to the stratification of the JNC VI was: A, 16.2%; B, 51.4%, and C, 32.4%. High risk on the Framingham in the various groups of the JNC VI was: A, 0%; B, 9.2%, and C, 56.3% (kappa, 0.533). High risk on the Sheffield in the groups of the JNC VI ran at: A, 4.2%; B, 41.3%, and C, 66.7% (kappa, 0.324). CONCLUSIONS: There was moderate concordance between the Framingham tables and the JNC VI for calculation of CR in our population.

¿Existe relación entre la valoración del riesgo coronario según las tablas de Framingham y Sheffield con la del sexto informe del Joint National Committee? Relación entre tablas de riesgo coronario / Is there a relationship between the assessment of coronary risk on the Framingham and Sheffield tables and the sixth report of the Joint National Commitee? Relationship between tables of coronary risk

Objetivo. Conocer la distribución del riesgo coronario (RC) de los distintos grupos de hipertensos del Joint National Committee ( JNC VI), tanto con la tabla de Framingham como con la de Sheffield, valorando si existe relación entre las diferentes escalas utilizadas.Diseño. Estudio descriptivo.Emplazamiento. ABS Tortosa Oeste. Tarragona. España.Participantes. Población rural hipertensa, de 30 a 74 años sin antecedentes de afección cardiovascular.Mediciones principales. Las variables estudiadas corresponden a la tabla de Anderson del estudio de Framingham, la de Sheffield y la del JNC VI. La concordancia se evalúa con el coeficiente kappa.Resultados. Se ha estudiado a 148 hipertensos con una edad media de 62 años, el 63,5 por ciento mujeres. El 23 por ciento presenta un RC alto según Framingham y el 42,1 por ciento, según Sheffield. La distribución de la muestra según la estratificación del JNC VI es: A, 16,2 por ciento; B, 51,4 por ciento; C, 32,4 por ciento. El porcentaje de riesgo alto según Framingham en los diferentes grupos de JNC VI es: A, 0 por ciento; B, 9,2 por ciento y C, 56,3 por ciento (kappa = 0,533). La distribución de riesgo alto de Sheffield en los grupos del JNC VI es: A, 4,2 por ciento; B, 41,3 por ciento y C, 66,7 por ciento (kappa = 0,324).Conclusiones. En nuestra población existe moderada concordancia en el cálculo del RC con las tablas de Framingham y del JNC VI (AU)

[Blood cholesterol in patients with cancer]. / Colesterol sérico en pacientes neoplásicos.

In a retrospective, descriptive and observational study realized between 1995 and January 1997 the seric levels cholesterol of 610 patients with cancer and 61 healthy ones, who were used as controls were revised. The serum cholesterol observed in the patients with cancer were lower than the ones observed in the healthy controls. These differences show and statistical significance. We could see in our study that cholesterol were lower in patients with disseminate disease than in the ones with localize disease and that had and statistical value. The number of patients included in each type of tumor, the seric cholesterol were lower than the ones obtained in the control group apart from the patients with metastasis in and unknown origin tumor which have not been significant.

[Results of treatment of Graves-Basedow disease with 131I at low calculated doses]. / Resultados del tratamiento de la enfermedad de Graves Basedow con 131I a dosis bajas calculadas.

OBJECTIVE: To evaluate the results of treatment of Graves' disease with 131I at low calculated doses. METHODS: A total of 333 patients with Graves' disease were treated with low calculated doses of 131I on the basis of thyroid size and 131I uptake (mean doses = 6.6 +/- 1.9 mCi). The mean follow-up was 24.4 months (range 12-145). RESULTS: The accumulated likelihood of hypothyroidism at 145 months of follow-up was 89.8% (Kaplan-Meier method) and relapse 26%. Pretreatment levels of T3 above 9 nmol/l were associated with a lower incidence of hypothyroidism (p = 0.049, Mantel-Cox method). Pretreatment levels of T4 above 300 nmol/l were associated with a higher risk of therapy failure (odds ratio 3.27; 95% confidence interval = 1.3-8.2, Cox method). Age, sex, previous therapy with anti-thyroid agents or surgery, 131I uptake, initial and total dose of 131I, number of administered doses and development of transient hypothyroidism were not predictive of the evolution of thyroid function. CONCLUSION: Therapy of hyperthyroidism (Graves' disease) with low calculated doses of 131I shows a high incidence of hypothyroidism, also increasing the cost involved in estimating the dose and long-term follow-up.

[Late diagnosis of heart rhabdomyoma with echocardiography]. / Diagnóstico tardío por ecocardiografía de rabdomioma cardíaco.

We describe 2 cases of tuberous sclerosis in a 17 and a 27 years old patients in which images compatible with a cardiac rhabdomioma were detected during an echocardiographic study. In one of the cases these images were multiple. We point out the few clinical repercussions they caused and the length of their undetected presence. We revise the clinical features and diagnosis of these rare tumours and comment on the need to withhold surgical treatment in situations which could put the patient's life in danger.