Integration of Triphenylene-Based Conductive Metal-Organic Frameworks into Carbon Nanotube Electrodes for Boosting Nonenzymatic Glucose Sensing.

The rational design and preparation of conductive metal-organic frameworks (MOFs) are alluring and challenging pathways to develop active catalysts toward electrocatalytic glucose oxidation. The hybridization of conductive MOFs with carbon nanotubes (CNTs) in the form of a composite can greatly improve the electrocatalytic performance. Herein, a facile one-step synthetic strategy is utilized to fabricate a Ni3(HHTP)2/CNT (HHTP = 2,3,6,7,10,11-hexahydroxytriphenylene) composite for nonenzymatic detection of glucose in an alkaline solution. The Ni3(HHTP)2/CNT composite, as an electrochemical glucose sensor material, exhibits superior electrocatalytic activity toward glucose oxidation with a wide detection range of up to 3.9 mM, a low detection limit of 4.1 µM (signal/noise = 3), a fast amperometric response time of <2 s, and a high sensitivity of 4774 µA mM-1 cm-2, surpassing the performance of some recently reported nonenzymatic transition-metal-based glucose sensors. In addition, the composite sensor also shows outstanding selectivity, robust long-term electrochemical stability, favorable anti-interference properties, and good reproducibility. This work displays the effectiveness of enhancing the electrocatalytic performance toward glucose detection by combing conductive MOFs with CNTs, thereby opening up an applicable and encouraging approach for the design of advanced nonenzymatic glucose sensors.

Bioactive Ion-Based Switchable Supercapacitors.

Switchable supercapacitors (SCs) enable a reversible electrically-driven uptake/release of bioactive ions by polarizing porous carbon electrodes. Herein we demonstrate the first example of a bioactive ion-based switchable supercapacitor. Based on choline chloride and porous carbons we unravel the mechanism of physisorption vs. electrosorption by nuclear magnetic resonance, Raman, and impedance spectroscopy. Weak physisorption facilitates electrically-driven electrolyte depletion enabling the controllable uptake/release of electrolyte ions. A new 4-terminal device is proposed, with a main capacitor and a detective capacitor for monitoring bioactive ion adsorption in situ. Ion-concentration control in printed choline-based switchable SCs realizes switching down to 8.3 % residual capacitance. The exploration of adsorption mechanisms in printable microdevices will open an avenue of manipulating bioactive ions for the application of drug delivery, neuromodulation, or neuromorphic devices.

Toxicity of oleate-based amino protic ionic liquids towards Escherichia coli, Danio rerio embryos and human skin cells.

Protic ionic liquids (PILs) have been widely employed with the label of "green solvents'' in different sectors of technology and industry. The studied PILs are promising for corrosion inhibition and lubrication applications in industry. Industrial use of the PILs can transform them in wastes, due to accidental spill or drag in water due to washing, that can reach water bodies. In addition, the handling of the product by the workers can expose them to accidental contact. Thus, the aim of this work is to evaluate the toxicity of PILs 2-hydroxyethylammonium oleate (2-HEAOl), N-methyl-2-hydroxyethylammonium oleate (m-2HEAOl) and bis-2-hydroxyethylammonium oleate (BHEAOl) towards Escherichia coli, zebrafish embryos, model organisms that can be present in water, and human skin cells. This is the first work reporting toxicity results for these PILs, which constitutes its novelty. Results showed that the studied PILs did not inhibit E. coli bacterial growth but could cause human skin cells death at the concentrations of use. LC50 values for zebrafish eggs were 40.21 mg/L for 2HEAOl, 12.92 mg/L for BHEAOl and 32.74 mg/L for m-2HEAOl, with sublethal effects at lower concentrations, such as hatching retarding, low heart rate and absence of free swimming.