Assuntos
Melanoma/secundário , Neoplasias Cutâneas/patologia , Transplante de Pele , Idoso , Antígenos de Neoplasias , Procedimentos Cirúrgicos Dermatológicos , Humanos , Masculino , Melanoma/patologia , Melanoma/cirurgia , Antígenos Específicos de Melanoma , Proteínas de Neoplasias/análise , Proteínas S100/análise , Pele/química , Pele/patologia , Neoplasias Cutâneas/cirurgiaRESUMO
Facial wrinkling is a marker of skin ageing. The association between smoking and facial wrinkling has been previously studied. Nevertheless, there are no reports assessing the role of sun exposure and smoking in an area with a great proportion of sunny days. Smoking habits were investigated in 282 healthy individuals. Facial wrinkles were measured according to the Daniell scale at the external canthus. A logistic regression model was developed controlling for age, sex, sun exposure, smoking habit and searching for the interaction between sun exposure and smoking. A statistically significant risk was found for smoking habit (OR = 3.1; 95% CL 1.28-7.76; p = 0.008), sun exposure (OR = 1.50; 95% Cl 1.25-1.80; p = 0.05), and age (OR = 1.18; 95% Cl 1.13-1.23; p = 0.024) for facial wrinkling. These results show the evidence of an accelerated skin ageing in smokers. A clear explanation given to smokers could be a useful strategy to persuade them to leave smoking.
Assuntos
Envelhecimento da Pele/efeitos dos fármacos , Fumar/efeitos adversos , Adulto , Idoso , Distribuição de Qui-Quadrado , Face , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Envelhecimento da Pele/efeitos da radiação , Espanha , Luz Solar/efeitos adversos , Fatores de TempoRESUMO
The association of malignant melanoma with different neoplasias is uncommon but not exceptional. We present two cases of malignant melanoma associated with lymphoma, and analyze the variety of etiopathogenic factors which have been implicated in both neoplasias, with special emphasis on those that may explain this association.
Assuntos
Doença de Hodgkin/complicações , Linfoma não Hodgkin/complicações , Melanoma/complicações , Neoplasias Cutâneas/complicações , Adulto , Feminino , Humanos , Terapia de Imunossupressão , Masculino , Melanoma/imunologia , Pessoa de Meia-Idade , Neoplasias Cutâneas/imunologiaRESUMO
A revision was carried out on all cases of dermatosis involving transepidermal elimination seen in the last 25 years in the Department of Medical Surgical Dermatology and Venereology, School of Medicine, University of Granada. The study included clinical-statistical, therapeutic, histopathologic and evolutional aspects. In the discussion the low incidence of perforating dermatoses in the Eastern Andalusian area is emphasized.
Assuntos
Doença de Darier/patologia , Foliculite/patologia , Dermatopatias Vesiculobolhosas/classificação , Adulto , Idoso , Colágeno/metabolismo , Tecido Elástico/patologia , Epiderme/patologia , Feminino , Corpos Estranhos/patologia , Granuloma/patologia , Humanos , Ceratoacantoma/patologia , Masculino , Pessoa de Meia-Idade , Necrobiose Lipoídica/patologia , Pele/patologia , Dermatopatias Vesiculobolhosas/patologia , Xantomatose/patologiaRESUMO
Twenty-three cases of subungual exostosis are described, representing an incidence of 0.031% in our setting. Children and adolescents were most frequently affected, with a clear predominance of females. Eight lesions were observed in exceptional locations, three on the fingers and five on the third and fourth toes. The results of the surgical technique employed to excise the exostosis are evaluated.
Assuntos
Exostose/patologia , Doenças da Unha/patologia , Adolescente , Fatores Etários , Criança , Doença Crônica , Feminino , Dedos , Humanos , Inflamação , Fatores Sexuais , Dedos do PéRESUMO
Seven observations of papulo-vesicular acrolocated syndromes in males between 6 months and three years age. Clinical, histological and nosological aspects are commented in according to Gianotti's words and last reports about this disease.
