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1.
Arch Esp Urol ; 69(9): 613-620, 2016 Nov.
Artigo em Espanhol | MEDLINE | ID: mdl-27845692

RESUMO

OBJECTIVES: To define the different characteristics of transdermal oxybutynin (TO) for the treatment of overactive bladder in adults, to know the barriers for the use of this drug and to establish proposals to minimize these barriers. METHODS: Local sessions were held with 111 urologists from all over the country divided into 12 sessions. They were moderated by a brainstorming technique led by an external consultant. RESULTS: 75% of experts believe that tolerability and clinical efficacy (50%) are the most important attributes to choose this formulation, being the lack of scientific publications the least valued (12%). These opinions were based on their own clinical experience with TO or on scientific publications, without establishing comparison with other treatment options. The main barriers would be administrative obstacles (84%), difficulty in its use (54%) and the lack/rejection of the transdermal administration by the patient (33%). Actions were proposed to correct the 8 most significant barriers, such as better training for specialists (both Urology and other specialties) and for patients, creating informative materials to reinforce health education in managing patches, generating greater volume of scientific evidence to support their use in overactive bladder and clearly identifying the profile of patients who will benefit most from this therapeutic strategy. CONCLUSIONS: Although oxybutynin has been standard treatment of overactive bladder in recent years the conclusion of this working group is that its new transdermal formulation offers a better-tolerated alternative for patients, and, therefore the necessary tools to generate more evidence should be implemented to increase the proper use among specialists and patients.


Assuntos
Prova Pericial , Ácidos Mandélicos/administração & dosagem , Antagonistas Muscarínicos/administração & dosagem , Bexiga Urinária Hiperativa/tratamento farmacológico , Administração Cutânea , Adulto , Humanos , Guias de Prática Clínica como Assunto , Espanha
2.
Arch. esp. urol. (Ed. impr.) ; 69(9): 613-620, nov. 2016. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-157665

RESUMO

OBJETIVO: Definir las características diferenciales de la oxibutinina transdérmica (OT) en el tratamiento de la vejiga hiperactiva en pacientes adultos, conocer las barreras de uso y establecer propuestas para minimizar estas barreras. MÉTODOS: Se realizaron 12 sesiones de ámbito local a las que acudieron 111 urólogos en total de todo el territorio nacional, que fueron moderadas mediante una técnica de brainstorming dirigida por un consultor externo. RESULTADOS: El 75% de los expertos opina que la tolerabilidad y la eficacia clínica (50%) son los 'atributos' más importantes para escoger esta formulación, siendo el menos valorado la escasez de publicaciones científicas (12%), basándose en su propia experiencia clínica con OT o la referida en publicaciones científicas, sin establecer comparación con otras alternativas de tratamiento. Las principales 'barreras' para su uso serían las trabas administrativas (84%), la dificultad en su manejo (54%) y el desconocimiento-rechazo de la vía transdérmica por parte del paciente (33%). Se acordaron acciones para subsanar las 8 barreras más significativas, como mayor formación para especialistas (tanto Urología como otras especialidades) y para pacientes, creación de materiales informativos para reforzar la educación en el manejo de parches, generar mayor volumen de evidencia científica que avale su uso en la vejiga hiperactiva e identificar claramente los perfiles de pacientes más beneficiarios de esta estrategia terapéutica. CONCLUSIONES: Este grupo de expertos identificó la tolerabilidad y eficacia como los dos atributos clave que debe tener un fármaco para el tratamiento de la vejiga hiperactiva, de los cuales la OT destaca en el primero de ellos. Además, deben emprenderse acciones formativas, educativas y de investigación a todos los actores implicados con el fin de superar las barreras que dificultan el correcto manejo de este fármaco


OBJECTIVES: To define the different characteristics of transdermal oxybutynin (TO) for the treatment of overactive bladder in adults, to know the barriers for the use of this drug and to establish proposals to minimize these barriers. METHODS: Local sessions were held with 111 urologists from all over the country divided into 12 sessions. They were moderated by a brainstorming technique led by an external consultant. RESULTS: 75% of experts believe that tolerability and clinical efficacy (50%) are the most important attributes to choose this formulation, being the lack of scientific publications the least valued (12%). These opinions were based on their own clinical experience with TO or on scientific publications, without establishing comparison with other treatment options. The main barriers would be administrative obstacles (84%), difficulty in its use (54%) and the lack/rejection of the transdermal administration by the patient (33%). Actions were proposed to correct the 8 most significant barriers, such as better training for specialists (both Urology and other specialties) and for patients, creating informative materials to reinforce health education in managing patches, generating greater volume of scientific evidence to support their use in overactive bladder and clearly identifying the profile of patients who will benefit most from this therapeutic strategy. CONCLUSIONS: Although oxybutynin has been standard treatment of overactive bladder in recent years the conclusion of this working group is that its new transdermal formulation offers a better-tolerated alternative for patients, and, therefore the necessary tools to generate more evidence should be implemented to increase the proper use among specialists and patients


Assuntos
Humanos , Parassimpatolíticos/uso terapêutico , Antagonistas Colinérgicos/uso terapêutico , Bexiga Urinária Hiperativa/tratamento farmacológico , Antagonistas Muscarínicos/uso terapêutico , Prova Pericial , Pesquisas sobre Atenção à Saúde/estatística & dados numéricos , Tolerância a Medicamentos , Resultado do Tratamento , Adesivo Transdérmico
3.
Arch Esp Urol ; 55(1): 79-81, 2002.
Artigo em Espanhol | MEDLINE | ID: mdl-11957759

RESUMO

OBJECTIVE: To report a case of leiomyoma of the bladder in a patient with unspecific urinary symptoms and discuss the utility of the diagnostic imaging techniques. METHODS/RESULTS: A 56-year-old woman who consulted for unspecific urinary symptoms is described. Patient evaluation with ultrasound, CT and MRI showed a mass in the posterior aspect of the urinary bladder. CONCLUSIONS: Leiomyoma of the bladder is an uncommon benign tumor that is asymptomatic in most of the cases and is frequently discovered incidentally during assessment for other conditions. The case described herein presented with unspecific urinary symptoms. Patient evaluation with different diagnostic imaging techniques was required for correct diagnosis and treatment.


Assuntos
Leiomioma/diagnóstico , Neoplasias da Bexiga Urinária/diagnóstico , Adulto , Feminino , Humanos , Leiomioma/diagnóstico por imagem , Leiomioma/patologia , Imageamento por Ressonância Magnética , Tomografia Computadorizada por Raios X , Neoplasias da Bexiga Urinária/diagnóstico por imagem , Neoplasias da Bexiga Urinária/patologia
4.
Arch. esp. urol. (Ed. impr.) ; 55(1): 79-81, ene. 2002.
Artigo em Es | IBECS | ID: ibc-11616

RESUMO

OBJETIVOS: Presentación de un caso de leiomioma vesical con sintomatología urinaria inespecífica, una patología muy poco frecuente y en la mayoría de los casos asintomática, con un estudio diagnostico por imagen que nos orienta hacia la patología del caso.MÉTODOS: Paciente de 56 años de edad que consulta por síntomas urinarios inespecíficos, que tras su estudio se diagnostica de masa en cara posterior de vejiga mediante ecografía, T.A.C. y R.M.N.CONCLUSIONES: El leiomioma vesical es un tumor benigno de baja incidencia que en la mayoría de los casos se diagnostica de forma incidental en el transcurso del estudio de otra especialidad u otra patología. El caso que nosotros presentamos debutó con clínica urinaria inespecífica y fue necesaria la realización de diversas técnicas de diagnostico por imagen hasta llegar a un correcto enfoque terapéutico del caso (AU)


Assuntos
Adulto , Feminino , Humanos , Tomografia Computadorizada por Raios X , Imageamento por Ressonância Magnética , Leiomioma , Neoplasias da Bexiga Urinária
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