RESUMO
Analysis of the radiotherapy's failures in a form of metastatic lymph nodes was performed in the group of 373 laryngeal cancer patients. The authors point out that irradiation of large metastatic lymph nodes do not produce satisfying results. In the cases with supraglottic involvement there is a need of elective total neck irradiation.
Assuntos
Neoplasias de Cabeça e Pescoço/secundário , Neoplasias Laríngeas/radioterapia , Laringe/efeitos da radiação , Linfonodos/patologia , Linfonodos/efeitos da radiação , Metástase Neoplásica , Humanos , Neoplasias Laríngeas/patologia , Laringe/patologia , Estadiamento de NeoplasiasRESUMO
The early and late local reactions after radiotherapy were evaluated by means of International Classification, in 345 laryngeal cancer patients. The positive correlation was found between the grade of reaction and radiation dose as so irradiated volume. The same tolerance was found in patients treated by X-therapy and cobalt teletherapy ++. The time for observation of the early reaction may be according to the authors elongated from 6 to 12 months.
Assuntos
Radioisótopos de Cobalto/efeitos adversos , Neoplasias Laríngeas/radioterapia , Lesões por Radiação/classificação , Teleterapia por Radioisótopo/efeitos adversos , Radioisótopos de Cobalto/administração & dosagem , Relação Dose-Resposta à Radiação , Humanos , Neoplasias Laríngeas/patologia , Estadiamento de Neoplasias , Lesões por Radiação/patologia , Tolerância a Radiação , Dosagem Radioterapêutica , Fatores de TempoRESUMO
A decrease in serum iron and total iron binding capacity (TIBC) has been seen in patients with various malignancies. Similar iron level and TIBC alterations we have found in patients with larynx cancer. Estimation of TIBC reflects the quantity of transferrin which is the iron carrier in serum. The serum iron and transferrin changes cannot be used for diagnostic purposes because they are not specific to malignancies. Such alterations have been also seen in inflammatory and infectious diseases, heart infarct and anaemias. However, it is of interest whether elimination of neoplastic tissue from an organism brings back the decreased serum iron and TIBC to normal values.