[Adult-onset of recurrent Coats disease]. / Enfermedad de Coats recidivante diagnosticada en sujeto adulto.

CASE REPORT: A male diagnosed with Coats disease at the age of 30 years, had a relapse of this condition 14 years later. His first symptom of blurred vision occurred in both episodes and similar findings of unilateral retinal exudation and lipid deposition at boundary were seen. Angiography showed the characteristic early hyperfluorescence of the telangiectasias and late leakage of dye. DISCUSSION: Coats disease is relatively uncommon and, as the degree of involvement varies from case to case, a randomized, prospective study of treatment would probably not be feasible. Despite the characteristic features of this disease, the differential diagnoses must be considered in both children and adults.

Enfermedad de Coats recidivante diagnosticada en sujeto adulto / Adult-onset of recurrent coats disease

Caso clínico: Paciente varón que con 30 años tuvo el primer episodio de enfermedad de Coats y recurrencia 14 años más tarde. Clínicamente ambos episodios tienen como síntoma de inicio visión borrosa y exploración típica de exudación masiva retiniana con corona de exudados duros. La angiografía presenta hallazgos característicos de telangiectasia retiniana con dilatación anormal de vasos con hiperfluorescencia precoz y fuga tardía. Discusión: Coats es una entidad clínica poco frecuente y con grado de severidad variable, que hacen difíciles los estudios randomizados prospectivos. Pese a los hallazgos característicos, hay que descartar otros diagnósticos tanto en el niño como en el adulto causantes de esa misma clínica

Case report: A male diagnosed with Coats disease at the age of 30 years, had a relapse of this condition 14 years later. His first symptom of blurred vision occurred in both episodes and similar findings of unilateral retinal exudation and lipid deposition at boundary were seen. Angiography showed the characteristic early hyperfluorescence of the telangiectasias and late leakage of dye. Discussion: Coats disease is relatively uncommon and, as the degree of involvement varies from case to case, a randomized, prospective study of treatment would probably not be feasible. Despite the characteristic features of this disease, the differential diagnoses must be considered in both children and adults

[Imiquimod in treatment of palpebral mycosis fungoides]. / Imiquimod como tratamiento de la micosis fungoide palpebral.

CLINICAL CASE: Our patient was a 37-year-old male with palpebral mycosis fungoides, the most common T-cell cutaneous lymphoma. He had been treated previously with topical corticosteroids. We treated him with Imiquimod cream (5%) three times a week. DISCUSSION: A clinical improvement was obtained with this drug, so we believe immuno-modulating agents need to be considered in the treatment of palpebral mycosis fungoides, especially because of its capacity of being a reflection of leukaemia.

Imiquimod como tratamiento de la micosis fungoide palpebral / Imiquimod in treatment of palpebral mycosis fungoides

Caso clínico: Presentamos el caso de un varón de37 años de edad que presentaba una micosis fungoide,el más frecuente de los linfomas T cutáneos,con localización exclusivamente palpebral quehabía sido tratado previamente con corticoides tópicos.Se instauró un tratamiento con Imiquimod al5% en crema tres veces semanales.Discusión: Con el uso de este medicamento, seconsiguió una gran mejoría clínica del paciente, porlo que consideramos muy importante tener en cuentaeste inmunomodulador para el tratamiento deesta enfermedad, de importancia por su capacidadde leucemización

Clinical case: Our patient was a 37-year-old male with palpebral mycosis fungoides, the most common T-cell cutaneous lymphoma. He had been treated previously with topical corticosteroids. We treated him with Imiquimod cream (5%) three times a week. Discussion: A clinical improvement was obtained with this drug, so we believe immuno-modulating agents need to be considered in the treatment of palpebral mycosis fungoides, especially because of its capacity of being a reflection of leukaemia