RESUMO
Cases of rhabdomyosarcoma (RMS) in 14 year old girls are described. The tumor was very aggressive with early and widespread metastases in regional and other lymph nodes, soft tissues, various parts of the skeleton, bone marrow, lungs. The diagnosis and spread of this tumour was established on the basis of total examination of the girls. Clinical stage III was found in one girl, stage IV in two patients with RMS of the breast. Diagnoses were confirmed histologically (open biopsy of the tumours). Bilateral alveolar RMS of the breast (synchronic or metachronic) was diagnosed in all the patients. Light and electron microscopies were insufficient for final diagnosis, histogenesis of the tumour was established by means of immunohistochemistry. All the patients died within 3 months to one year and half after diagnosis.
Assuntos
Neoplasias da Mama/diagnóstico , Rabdomiossarcoma Alveolar/diagnóstico , Adolescente , Biomarcadores Tumorais/análise , Biomarcadores Tumorais/metabolismo , Neoplasias da Mama/patologia , Feminino , Humanos , Metástase Linfática , Estadiamento de Neoplasias , Rabdomiossarcoma Alveolar/patologiaRESUMO
A computer analyzer is regularly used in the department of pathology in formalized macrodescription of the stomach. Advantages of this method are described.
Assuntos
Diagnóstico por Computador , Patologia Clínica , Estômago/patologia , Algoritmos , Diagnóstico por Computador/instrumentação , Diagnóstico por Computador/métodos , Humanos , Patologia Clínica/instrumentação , Patologia Clínica/métodos , SoftwareRESUMO
The interaction between Y. pseudotuberculosis and different representatives of the aqueous and, partially, soil biocenosis was studied. The study revealed that invertebrates of the plankton and benthos (water fleas, cyclops, mollusks, Oligochaeta, larvae of insects), as well as fish and higher plants, ensured the prolonged existence of Yersinia in water. Thus hydrobiotic organisms were to be regarded as potential natural hosts of Y. pseudotuberculosis. A suggestion was made that fish, the final link of some alimentary chains, could present epidemic danger as a food product for human consumption.
Assuntos
Ecossistema , Microbiologia da Água , Yersinia pseudotuberculosis/fisiologia , Animais , Peixes/microbiologia , Plâncton , Plantas/microbiologia , Fatores de Tempo , Yersinia pseudotuberculosis/isolamento & purificaçãoRESUMO
The virus-inhibiting and immunostimulating activity of Soviet preparations, maleic anhydride copolymers, was demonstrated in alpha-, flavi-, and bunyavirus infections. Positive results were obtained in subcutaneous and intraperitoneal inoculations of the preparations used in prophylactic and therapeutic-prophylactic schedules. Stimulation of vaccination immunity was observed after combined use of copolymers and the vaccine against Eastern equine encephalomyelitis.