[Debatable questions of strophanthin and spironolactone treatment in certain forms of acute myocardial infarct]. / Spornye voprosyu lecheniia strofantinom i spironolaktonami bol'nykh s nekotorymi formami ostrogo infarkta miokarda.

The results of clinical and instrumental examination of 67 patients and experimental findings provide evidence of myocardial resistance to cardiac glycosides in acute myocardial infarction complicated by the initial stage of cardiac insufficiency. It is suggested that symptoms of secondary hyperaldosteronism may develop in acute myocardial infarction and that medication with cardiac glycosides in combination with spironolactones is expedient.

[Prevention of lung and heart failure in chronic nonspecific respiratory organ diseases]. / Profilaktika legochnoi i serdechnoi nedostatochnosti u bol'nykh khronicheskimi nespetsificheskimi zabolevaniiami organov dykhaniia.

One-year dispensary surveillance and preventive treatment in patients with chronic nonspecific diseases of the respiratory organs and analysis of the results of dynamic examination by means of pneumotachometry, spirography and contact phlebography proved the high efficacy of dispensary care in the prevention of pulmonary and right-ventricular cardiac insufficiency.

[Initial stage of cardiac insufficiency as a complication of a past myocardial infarct]. / Nachal'naia stadiia serdechnoi nedostatochnosti kak oslozhnenie perenesennogo infarkta miokarda

An instrumental and roentgenological examination was conducted in 164 patients who had survived myocardial infarction 1 to 10 years before the examination and having been free of any clinically manifest signs of congestive heart failure. The investigation included a study of the inotropic and pump function of the myocardium of the left ventricle, the electric and mechanical activity of the left atrium, the pulmonary haemodynamics under bicycle tests of growing power, and under identical conditions after premedication with cardiac glycosides (0.00036 mg/kg of body weight of Strophanthin K). Proceeding from the study of the readaptation of the circulation system and its transit to the initial stage of cardiac insufficiency the authors developed criteria of the onset of therapy for latent cardiac failure in patients with postinfarction cardiosclerosis.