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1.
Artigo em Inglês | MEDLINE | ID: mdl-38829320

RESUMO

When participants study items one-by-one and are directed to either remember or forget the respective item directly after its presentation, retention of to-be-forgotten items is regularly worse than of to-be-remembered items. We tested whether this directed forgetting effect which is regularly observed for item memory generalizes to source memory. In three experiments, participants studied items in two different source colors (N = 101) or at two different source locations (N = 64; N = 81). Sources were manipulated orthogonally to item type (remember vs. forget). At test, we asked participants to recognize all studied items and also to identify their source. We used a multinomial processing tree model to disentangle item memory, source memory, and guessing. In all three experiments, we replicated the directed forgetting effect in item memory. Source memory for to-be-forgotten items that were recognized despite the intention to forget, however, tended to be even better than source memory for to-be-remembered items that were recognized. These results suggest that the directed forgetting effect does not simply translate from item to source memory. Rather source memory seems to be disproportionally increased in to-be-forgotten items that are remembered. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

2.
BMC Surg ; 10: 17, 2010 Jun 03.
Artigo em Inglês | MEDLINE | ID: mdl-20525275

RESUMO

BACKGROUND: Few patients with lung metastases from colorectal cancer (CRC) are candidates for surgical therapy with a curative intent, and it is currently impossible to identify those who may benefit the most from thoracotomy. The aim of this study was to determine the impact of various parameters on survival after pulmonary metastasectomy for CRC. METHODS: We performed a retrospective analysis of 40 consecutive patients (median age 63.5 [range 33-82] years) who underwent resection of pulmonary metastases from CRC in our institution from 1996 to 2009. RESULTS: Median follow-up was 33 (range 4-139) months. Twenty-four (60%) patients did not have previous liver metastases before undergoing lung surgery. Median disease-free interval between primary colorectal tumor and development of lung metastases was 32.5 months. 3- and 5-year overall survival after thoracotomy was 70.1% and 43.4%, respectively. In multivariate analysis, the following parameters were correlated with tumor recurrence after thoracotomy; a history of previous liver metastases (HR = 3.8, 95%CI 1.4-9.8); and lung surgery other than wedge resection (HR = 3.0, 95%CI 1.1-7.8). Prior resection of liver metastases was also correlated with an increased risk of death (HR = 5.1, 95% CI 1.1-24.8, p = 0.04). Median survival after thoracotomy was 87 (range 34-139) months in the group of patients without liver metastases versus 40 (range 28-51) months in patients who had undergone prior hepatectomy (p = 0.09). CONCLUSION: The main parameter associated with poor outcome after lung resection of CRC metastases is a history of liver metastases.


Assuntos
Causas de Morte , Neoplasias Colorretais/patologia , Neoplasias Hepáticas/mortalidade , Neoplasias Hepáticas/secundário , Neoplasias Pulmonares/mortalidade , Neoplasias Pulmonares/secundário , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Neoplasias Colorretais/mortalidade , Feminino , Hepatectomia/métodos , Hepatectomia/mortalidade , Humanos , Neoplasias Hepáticas/cirurgia , Modelos Logísticos , Neoplasias Pulmonares/patologia , Neoplasias Pulmonares/cirurgia , Masculino , Pessoa de Meia-Idade , Pneumonectomia/métodos , Pneumonectomia/mortalidade , Valor Preditivo dos Testes , Probabilidade , Estudos Retrospectivos , Medição de Risco , Análise de Sobrevida
3.
Surg Laparosc Endosc Percutan Tech ; 19(1): e26-8, 2009 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-19238053

RESUMO

We present a case of an asymptomatic 76-year-old woman treated laparoscopically for an urachal mucocele owing to a nonmetastatic urachal mucinous adenocarcinoma. Since laparoscopic en bloc resection of the urachus and partial cystectomy, the patient has been healthy and disease-free for 12 months. Modern surgical treatment of urachal adenocarcinoma is discussed in the light of this case.


Assuntos
Adenocarcinoma Mucinoso/cirurgia , Cistectomia/métodos , Laparoscopia , Mucocele/cirurgia , Cisto do Úraco/cirurgia , Adenocarcinoma Mucinoso/patologia , Idoso , Feminino , Humanos , Mucocele/patologia , Cisto do Úraco/patologia
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