RESUMO
A 46-year-old man presented with Aspergillus fumigatus spondylodiscitis after lumbar surgery. He was successfully treated with the new antifungal drug itraconazole in combination with surgical débridement of the disc space. The patient has remained on itraconazole for more than a year and tolerated the drug well.
Assuntos
Antifúngicos/uso terapêutico , Aspergilose/tratamento farmacológico , Aspergillus fumigatus , Discite/tratamento farmacológico , Cetoconazol/análogos & derivados , Vértebras Lombares , Infecção da Ferida Cirúrgica/tratamento farmacológico , Terapia Combinada , Desbridamento , Discite/cirurgia , Humanos , Itraconazol , Cetoconazol/uso terapêutico , Masculino , Pessoa de Meia-Idade , Infecção da Ferida Cirúrgica/cirurgiaRESUMO
We are reporting on a 36-year-old man with septicemia and a liver abscess due to Actinomyces sp. The infection was most probably acquired while eviscerating a deer he had shot. The possibility of an infection involving Actinomyces bovis is discussed. The liver abscess was diagnosed on the basis of non-invasive procedures. Therapy consisted of high-dose penicillin without surgical drainage of the abscess. The infection did not recur during the three-and-a-half year follow-up period. No previous reports of successful antibiotic therapy for actinomycotic liver abscess without surgical procedures are known.