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Int J Numer Method Biomed Eng ; 38(1): e3538, 2022 01.
Artigo em Inglês | MEDLINE | ID: mdl-34617416

RESUMO

Diffuse optical tomography is a non-invasive and non-irradiating medical imaging technique that is particularly suitable for cerebral monitoring of newborns since it can be used at the bedside of the patient. Here, a new model for optical tomography in the neonatal brain is presented that takes into account the presence of arachnoid trabeculae in the cerebrospinal fluid (CSF). It is known that the classical diffusion approximation (DA) for light propagation is at the limit of validity in the CSF layer due to the low values of the absorption and scattering coefficients. The new model is obtained by the DA of the homogenized radiative transfer equation and is rigorously justified. Numerical results in two and three dimensions attest for the improved sensitivity of the new model to the presence of perturbations in the brain layer.


Assuntos
Luz , Tomografia Óptica , Simulação por Computador , Cabeça/diagnóstico por imagem , Humanos , Recém-Nascido , Espalhamento de Radiação , Tomografia Óptica/métodos
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