RESUMO
Four new water-soluble constituents, oblongaroside A (1), oblongar ester A (2), oblongaroside B (3), and oblongaroside C (4), were isolated along with four known compounds: 4-O-beta-D-glucopyranosyl-3-hydroxybenzalcohol (5), 7-methoxyl-4-O-beta-D-glucopyranosyl-3-hydroxybenzalcohol (6), 4-O-beta-D-glucopyranosyl-3-hydroxybenzoic acid (7), and 3,4-dihydroxybenzoic acid (8) from the leaves of Ilex oblonga. Identification of their structures was achieved by 1D and 2D NMR experiments, including (1)H-(1)H COSY, NOESY, HMQC, and HMBC methods and FAB mass spectral data.
Assuntos
Ácidos Cafeicos/isolamento & purificação , Glucosídeos/isolamento & purificação , Hidroxibenzoatos/isolamento & purificação , Ilex/química , Folhas de Planta/química , Ácidos Cafeicos/química , Glucosídeos/química , Hidroxibenzoatos/química , Espectroscopia de Ressonância MagnéticaRESUMO
Three new water-soluble constituents [ficuscarpanoside B (1), (7E,9Z)-dihydrophaseic acid 3-O-beta-D-glucopyranoside (4) and ficuscarpanic acid (6)] and the natural product 2,2'-dihydroxyl ether (7) have been isolated, together with three known compounds [(7S,8R)-syringoylglycerol (2), (7S,8R)-syringoylglycerol-7-O-beta-D-glucopyranoside (3) and icariside D2 (5)] from the aerial roots of Ficus microcarpa. Identification of their structures was achieved by 1D and 2D NMR experiments, including 1H-1H COSY, NOESY, HMQC and HMBC methods and FAB mass spectral data.
Assuntos
Compostos Bicíclicos Heterocíclicos com Pontes/química , Ácidos Dicarboxílicos/química , Ácidos Graxos Insaturados/química , Ficus/química , Glucosídeos/química , Glicosídeos/química , Reguladores de Crescimento de Plantas/química , Raízes de Plantas/química , Plantas Medicinais/química , Compostos Bicíclicos Heterocíclicos com Pontes/isolamento & purificação , Cromatografia , Ácidos Dicarboxílicos/isolamento & purificação , Ácidos Graxos Insaturados/isolamento & purificação , Glucosídeos/isolamento & purificação , Glicosídeos/isolamento & purificação , Estrutura Molecular , Reguladores de Crescimento de Plantas/isolamento & purificação , Espectrofotometria , TaiwanRESUMO
Eight new triterpenoid saponins, kudinosides I-P along with three known saponins were isolated from the leaves of Ilex kudincha. The aglycone moiety of kudinosides I-K was determined as a new triterpene (kudinolic acid), a fore-genin for the lactonic triterpene. The structures of all saponins were established on the basis of spectroscopic and chemical evidence. The biogenesis of the triterpene with lactonic moiety was briefly discussed.
Assuntos
Medicamentos de Ervas Chinesas/química , Plantas Medicinais/química , Saponinas/química , Saponinas/isolamento & purificação , Triterpenos/química , Triterpenos/isolamento & purificação , Cromatografia Líquida de Alta Pressão , Espectroscopia de Ressonância Magnética , Espectrometria de Massas , Estrutura Molecular , Folhas de Planta/química , Espectrofotometria Infravermelho , Estereoisomerismo , Relação Estrutura-AtividadeRESUMO
Three new triterpenoid saponins, latifolosides F, G, H were isolated from the leaves of Ilex latifolia. Their structures were elucidated on the basis of chemical and spectral evidence. Latifoloside F was determined to be 3-O-[alpha-L-rhamnopyranosyl(1-2)]-[beta-D-glucopyranosyl(1-3)-]- alpha-L-arabinopyranosyl ilexgenin B 28-O-[alpha-L-rhamnopyranosyl(1-2)]-beta-D-glucopyranoside. Latifoloside G was 3-O-[alpha-L-rhamnopyranosyl(1-2)]-[beta-D-glucopyranosyl(1-3)-]- alpha-L-arabinopyranosyl pomolic acid 28-O-[alpha-L-rhamnopyranosyl(1-2)]-beta-D-glucopyranoside. Latifolioside H(3) was 3-O-[alpha-L-rhamnopyranosyl(1-2)]-[beta-D-glucopyranosyl(1-3)-]- alpha-L-arabinopyranosyl siaresinolic acid 28-O-[alpha-L-rhamnopyranosyl(1-2)]-beta-D-glucopyranoside.
Assuntos
Plantas/química , Saponinas/isolamento & purificação , Triterpenos , Configuração de Carboidratos , Sequência de Carboidratos , Espectroscopia de Ressonância Magnética , Dados de Sequência Molecular , Saponinas/química , Espectrometria de Massas de Bombardeamento Rápido de ÁtomosRESUMO
Three new saponins, named kudinosides A, B and C, were isolated from the leaves of Ilex kudincha. On the basis of spectroscopic analysis and chemical transformation their structures were elucidated as 3-O-beta-D-glucopyranosyl-(1-->3)-[alpha-L-rhamnopyranosyl- (1-->2)]-alpha-L-arabinopyranosyl-beta-kudinlactone, 3-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->3)-alpha-L- arabinopyranosyl-beta-kudinlactone and 3-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->3)-[alpha-L -rhamnopyranosyl-(1-->2)]-alpha-L-arabinopyranosyl-beta-kudinla c tone.
Assuntos
Plantas Medicinais , Saponinas/química , Triterpenos/química , Configuração de Carboidratos , Sequência de Carboidratos , Espectroscopia de Ressonância Magnética , Medicina Tradicional Chinesa , Dados de Sequência Molecular , Estrutura Molecular , Rotação Ocular , Folhas de Planta , Saponinas/isolamento & purificação , Triterpenos/isolamento & purificaçãoRESUMO
Two new triterpenes, alpha- and beta-kudinlactone, and six new triterpenoid glycosides, kudinosides D-G, I and J, were isolated from the leaves of Ilex kudincha. Their structures have been elucidated by spectroscopic and chemical means.
