Central corneal thickness and intraocular pressure in the Cameroonian nonglaucomatous population.

AIM: We performed a prospective, analytical study from 01 January to 31 March 2009 in the Ophthalmology Unit of the Gyneco-Obstetric and Pediatric Hospital of Yaounde, aiming to determine the profile of central corneal thickness (CCT) in the Cameroonian nonglaucomatous black population and its relationship with intraocular pressure (IOP). RESULTS AND DISCUSSION: Four hundred and eighty-five patients (970 eyes) meeting our inclusion criteria were selected for this study. The average CCT was 529.29 +/- 35.9 mum in the right eye (95% confidence interval [CI]: 526.09-532.49), 528.19 +/- 35.9 mum in the left eye (95% CI: 524.99-531.40) and 528.74 +/- 35.89 mum in both eyes (95% CI: 526.48-531.00), range 440 to 670 mum. The average IOP was 13.01 +/- 2.97 mmHg in both eyes (95% CI: 12.82-13.19). A rise in CCT by 100 mum was followed by an increase in IOP of about 2.8 mmHg (95% CI: 2.3-3.6) for both eyes taken together. Linear regression analysis showed that corneal thickness was negatively correlated with age and IOP was positively related with age. CONCLUSION: CCT in the Cameroonian nonglaucomatous black population was found to be lower compared with CCT values in Caucasian and Asian populations. On the basis of reference values ranging between 527 and 560 mum, an adjustment of IOP values by a correction factor is required for many Cameroonian patients. This will improve the diagnosis and follow-up of glaucoma by helping to detect true ocular hypertension.

[Eye disease in children aged 6 to 15 years: a hospital-based study in Yaounde]. / La pathologie oculaire de l'enfant âgé de 6 à 15 ans: étude hospitalière à Yaoundé.

UNLABELLED: This prospective study was conducted in the ophthalmology department of the Gynaeco-Obstetric and Paediatric Hospital in Yaoundé and included 422 children recruited from January to April 2008. The aim was to identify the eye diseases seen frequently seen in school-aged children from 6 to 15 years and examine their epidemiological characteristics. RESULTS AND DISCUSSION: The study group included 201 boys and 221 girls, with a mean age of 10,3 +/- 3.2 years. The most frequent disease was ametropia (refractive errors, 43.1%), including hyperopia, which had a prevalence of 23.7% Conjunctival disorders came next, accounting for 33%, more than half due to tropical endemic limbo conjunctivitis (17.8%). Binocular blindness affected 0.9% (n = 4), and low vision 0.7% (n = 3). CONCLUSION: This study, the first in its kind for the age group of 6-15 years in a developing country, allowed us to identify refractive errors as the principal complaint in consultations and led us to propose a reinforcement of screening in schools.

Prevalence and etiologies of visual handicaps in leprosy patients in the south of Cameroon.

UNLABELLED: We report on a prospective study undertaken in April 2008, in 11 leper villages of the Southern Cameroon. Our aim was to determine the prevalence and the causes of bilateral blindness, low vision and unilateral blindness in the population of leprosy patients, irrespective of the clinical aspects of the illness. RESULTS: Two hundred thirty-five known and newly diagnosed leprosy patients were examined. These patients included 149 cases (63.4%) of multibacillary leprosy and 86 cases (36.6%) of paucibacillary leprosy. There were 111 case of visual handicap, representing 47.2% of the population. These visual handicap cases were subdivided into 45 cases (19%) of bilateral blindness, 35 cases (15%) of unilateral blindness and 31 cases (13.2%) of low vision. DISCUSSION: The prevalence of visual handicap among leprosy patients in Cameroon is too high. Causes in the majority of cases are age-related degenerative pathologies, and one third of cases are linked to the leprosy mycobacterium. CONCLUSION: Discovering a cure for ophthalmic pathologies is important in order to provide a better quality of life for this particular population.

[Clinical and epidemiological characteristics of chronic open angle glaucoma at a Yaoundé Hospital]. / Caractéristiques cliniques et épidémiologiques du glaucome chronique à angle ouvert.

UNLABELLED: This retrospective study examined the files of patients who consulted at the Women's and Children's Hospital of Yaoundé in Cameroon from March 2003 through December 2006. The main objective was to determine the epidemiological and clinical characteristics of patients diagnosed with chronic open-angle glaucoma (COAG). RESULTS: Of 8,123 files reviewed, 184 patients (54.3% women) were diagnosed with COAG, all but one binocular. Their mean age was 62.2+/-13.01 years. According to the WHO definition of blindness, the rate of bilateral blindness was 34.2%, that of unilateral blindness 21% and low vision 17.4%. Significant statistic correlations were observed between the cup depth of the optic disc and visual acuity on one hand, and between the level of intraocular pressure and cup depth on the other, p=0.0001. Approximately 90.67% of the eyes with glaucoma had high pressure and 9.23% normal pressure. DISCUSSION: COAG is a major cause of visual disability in Cameroon. Intraocular pressure is an important risk factor, but its positive predictive value for the impairment of optic disc fibres is low (R=0.29); other factors (apoptosis and ischemia of the optic disc) are associated with it. CONCLUSION: Advanced strategies for early diagnosis of COAG are essential, for this disease is an important cause of blindness. Such programmes would significantly delay the onset of visual disabilities.

Intraocular live male filarial Loa loa worm.

We report a case of Loa loa filariasis in an 8-month-old child who presented with a 3-month history of irritated acute red eye and insomnia. Examination revealed a living and active adult Loa loa worm in the anterior chamber of the left eye. The worm was extracted under general anesthetic.