[Comparison of immunocytochemical and immunohistochemical methods for biomarker detection in breast cancer]. / Sravnenie immunotsitokhimicheskogo i immunogistokhimicheskogo metodov opredeleniia biomarkerov pri rake molochnoi zhelezy.

The detection of the biological parameters of the tumor before the treatment beginning becomes of more importance. The present study aimed to carry out the comparative analysis of the molecular markers expression (P53, Ki-67, Her-2/neu, Bcl-2, Bax, ER, FasL and CD95) at the cytologic and the correspondent histologic samples. The 18 tissue samples of the breast cancer were investigated. The immunocytochemical and the immunohistochemical methods of the molecular markers determination were used. Our study showed the correlation between two methods and the possibility of the use of the immunocytochemical staining as routine method of the molecular markers expression determination.