Dieta baja en grasas tras colecistectomía: ¿se debería recomendar de forma sistemática? / Low-fat diet after cholecystectomy: Should it be systematically recommended?

Introducción: A pesar de la falta de evidencia, tradicionalmente se ha recomendado seguir una dieta baja en grasas tras la colecistectomía. El objetivo principal fue analizar la correlación potencial entre los síntomas postoperatorios y el tipo de dieta tras la colecistectomía. Métodos: Los síntomas fueron evaluados de forma prospectiva mediante el cuestionario Gastrointestinal Quality of Life Index (GIQLI) antes de la intervención, al mes y 6 meses después de la colecistectomía en 83 pacientes operados en nuestro centro. Los pacientes completaron un cuestionario sobre su dieta y fueron clasificados en 4 grupos de acuerdo a la cantidad de grasa ingerida. Las diferencias en la puntuación GIQLI dependiendo del tipo de dieta se evaluaron en el tiempo. Resultados: La puntuación GIQLI total y varias dimensiones aumentaron significativamente tras la cirugía respecto al valor basal, independientemente de la ingesta de grasa en la dieta. Entre los síntomas evaluados por el GIQLI, la diarrea y la urgencia defecatoria empeoraron mientras que el estreñimiento mejoró. Más del 50% de los pacientes experimentaron cambios en el ritmo deposicional después de la cirugía, que fueron persistentes durante 6 meses en el 23% de los casos. Conclusiones: La dieta baja en grasas no parece influir en la mejoría de los síntomas tras la colecistectomía. No obstante, los resultados de un estudio aleatorizado que se está realizando en nuestro centro contribuirán a confirmar los resultados de este estudio prospectivo

Introduction: Even though evidence is lacking, a low-fat diet has been traditionally recommended after cholecystectomy. The main aim of this study was to assess the potential correlation between postoperative symptoms and type of diet after cholecystectomy. Methods: Symptoms were prospectively assessed by the Gastrointestinal Quality of Life Index (GIQLI) score at baseline, one month and 6 months after cholecystectomy in 83 patients operated on at our institution. Patients completed a questionnaire about their diet and were classified into 4 groups according to the amount of fat intake. Differences in the GIQLI score depending on the type of diet were assessed over time. Results: The overall GIQLI score and most subdomains significantly increased after surgery compared to baseline, regardless of the intake of dietary fat. Constipation improved after cholecystectomy compared to baseline, whereas diarrhea and bowel urgency got worse. More than 50% of patients experienced a change in their bowel habit after surgery, which persisted 6 months later in 23% of cases. Conclusions: A low fat diet does not seem to have an influence on the improvement of symptoms after cholecystectomy. However, a randomized study is ongoing at our institution to confirm the results of this prospective study

Low-fat diet after cholecystectomy: Should it be systematically recommended? / Dieta baja en grasas tras colecistectomía: ¿se debería recomendar de forma sistemática?

INTRODUCTION: Even though evidence is lacking, a low-fat diet has been traditionally recommended after cholecystectomy. The main aim of this study was to assess the potential correlation between postoperative symptoms and type of diet after cholecystectomy. METHODS: Symptoms were prospectively assessed by the Gastrointestinal Quality of Life Index (GIQLI) score at baseline, one month and 6 months after cholecystectomy in 83 patients operated on at our institution. Patients completed a questionnaire about their diet and were classified into 4 groups according to the amount of fat intake. Differences in the GIQLI score depending on the type of diet were assessed over time. RESULTS: The overall GIQLI score and most subdomains significantly increased after surgery compared to baseline, regardless of the intake of dietary fat. Constipation improved after cholecystectomy compared to baseline, whereas diarrhea and bowel urgency got worse. More than 50% of patients experienced a change in their bowel habit after surgery, which persisted 6 months later in 23% of cases. CONCLUSIONS: A low fat diet does not seem to have an influence on the improvement of symptoms after cholecystectomy. However, a randomized study is ongoing at our institution to confirm the results of this prospective study.

Determinants of Severity in Acute Pancreatitis: A Nation-wide Multicenter Prospective Cohort Study.

OBJECTIVE: The aim of this study was to compare and validate the different classifications of severity in acute pancreatitis (AP) and to investigate which characteristics of the disease are associated with worse outcomes. SUMMARY OF BACKGROUND DATA: AP is a heterogeneous disease, ranging from uneventful cases to patients with considerable morbidity and high mortality rates. Severity classifications based on legitimate determinants of severity are important to correctly describe the course of disease. METHODS: A prospective multicenter cohort study involving patients with AP from 23 hospitals in Spain. The Atlanta Classification (AC), Revised Atlanta Classification (RAC), and Determinant-based Classification (DBC) were compared. Binary logistic multivariate analysis was performed to investigate independent determinants of severity. RESULTS: A total of 1655 patients were included; 70 patients (4.2%) died. RAC and DBC were equally superior to AC for describing the clinical course of AP. Although any kind of organ failure was associated with increased morbidity and mortality, persistent organ failure (POF) was the most significant determinant of severity. All local complications were associated with worse outcomes. Infected pancreatic necrosis correlated with high morbidity, but in the presence of POF, it was not associated to higher mortality when compared with sterile necrotizing pancreatitis. Exacerbation of previous comorbidity was associated with increased morbidity and mortality. CONCLUSION: The RAC and DBC both signify an advance in the description and differentiation of AP patients. Herein, we describe the complications of the disease independently associated to morbidity and mortality. Our findings are valuable not only when designing future studies on AP but also for the improvement of current classifications.