1.
Angew Chem Int Ed Engl
; 39(1): 145-148, 2000 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10649356
RESUMO
Recursive deconvolution of a 729-membered peptide library has identified three active sequences, in which both Ser and His are present in one of the two tripeptidic chains generated on a steroidal scaffold (see structural formula), for the cleavage of an activated p-nitrophenyl ester. This combinatorial approach aims at searching for serine-protease-like activity.