[Postcoital contraception in primates. I. Action mechanism of a potential postovulatory fertility-inhibiting substance STS 456 in the baboon (Papio hamadryas)]. / Postkoitale Kontrazeption bei Primaten. I. Zum Wirkungsmechanismus einer potentiellen postovulatorisch fertilitätshemmenden Substanz STS 456 beim Pavian (Papio hamadryas)

With the substance STS 456, an estrogenic active steroid, a high fertility inhibition could be obtained in the pavian, when administered p. o. over a 5 day period postcoital. The effectiveness and also the side effects were dose dependent. The antifertility mechanism is based on an luteolytic effect, demonstrated by analytical hormonal investigations. The inhibition of the synthesis of steroids in the ovary affected not only progesterone but also the estrogens.

[Characteristics of the ovarianc cycle in the baboon (Papio hamadryas)]. / Charakteristika des Ovarialzyklus beim Pavian (Papio hamadryas).

The dynamics of estradiol, estrone, 17 alpha-hydroxyprogesterone, progesterone and 20 alpha-dihydroprogesterone were investigated in the blood plasma of the pavian (papio, hamadryas) with regard to the menstrual cycle and in comparison with the human. Furthermore results were presented about the basal temperature, the fern phenomenon and the development of the sex-skin in the pavian.