RESUMO
Background: COVID-19 is an infectious pathology that shows vascular changes during pregnancy, as well as in the placentas. The main objectives of this study were to estimate the prevalence and the risk factors for preeclampsia in hospitalized pregnant women with COVID-19. As well as comparing maternal and perinatal outcomes in hospitalized pregnant women with COVID-19 and preeclampsia with those without preeclampsia. Methods: Prospective cohort study of 100 hospitalized pregnant women from two tertiary hospitals, diagnosed with COVID-19, and divided into two groups: PE+ group (pregnant women with COVID-19 and preeclampsia) and PE- group (pregnant women with COVID-19 without preeclampsia). These pregnant women had prevalence, risk factors, maternal and perinatal data analyzed. Results: The prevalence of preeclampsia was 11%. Severe COVID-19 was the main risk factor for preeclampsia (OR = 8.18 [CI 1.53-43.52]), as well as fetal growth restriction was the main perinatal outcome (OR = 8.90 [CI 1.52-38.4]). Comorbidities were more frequent in the PE+ group (63.6% vs 31.5%, p = 0.03), as well as prematurity (81.8% vs 41.6%, p = 0.02), low birth weight (63.6% vs 24.7%, p = 0.01), and the need for neonatal intensive care admission of the newborn (63.6% vs 27.0%, p = 0.03). Pregnant women with PE had twice as long a length of stay in the intensive care unit (RR = 2.35 [CI 1.34-4.14]). Although maternal mortality was more frequent among pregnant women with PE, it was not statistically significant. Conclusions: Prevalence of preeclampsia in hospitalized pregnant women with COVID-19 was 11%. Severe COVID-19 was the main risk factor for preeclampsia and associated comorbidities increased the risk for developing preeclampsia. Long length of stay in the intensive care unit was the main maternal outcome and fetal growth restriction was the main perinatal outcome of preeclampsia.
Assuntos
COVID-19 , Pré-Eclâmpsia , Complicações Infecciosas na Gravidez , Resultado da Gravidez , SARS-CoV-2 , Centros de Atenção Terciária , Humanos , Gravidez , Feminino , Pré-Eclâmpsia/epidemiologia , COVID-19/epidemiologia , COVID-19/mortalidade , Brasil/epidemiologia , Estudos Prospectivos , Adulto , Complicações Infecciosas na Gravidez/epidemiologia , Complicações Infecciosas na Gravidez/virologia , Fatores de Risco , Resultado da Gravidez/epidemiologia , Prevalência , Recém-Nascido , Retardo do Crescimento Fetal/epidemiologia , Retardo do Crescimento Fetal/virologia , ComorbidadeRESUMO
A obesidade é uma doença crônica, cuja prevalência vem sobrepujando a desnutrição e as doenças infecciosas tanto em países desenvolvidos quanto nos em desenvolvimento, segundo a Organização Mundial da Saúde (OMS)1.Gordura abdominal total (GAT) representa um fator de risco cardiovascular. O estudo teve o objetivo de estabelecer uma associação de métodos não invasivos capazes de estimar a GAT. Foi avaliada a composição corporal de adultos (29-61 anos) obesos hipertensos (20M, 20F).A análise corporal foi realizada por meio de antropometria, bioimpedância elétrica (BIA) e tomografia computadorizada(TC). ..
Total abdominal fat (TAF) is a cardiovascular risk factor. The objective of this study was to establish an association of non-invasive methods able to estimate the total body fat. Body composition was assessed in obese hypertensive (20M, 20F) adults (29-61 years). Body analysis included anthropometry, bioelectrical impedance (BIA) and computed tomography (CT)...