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2.
Artigo em Inglês | MEDLINE | ID: mdl-34804404

RESUMO

Dermatomyositis (DM) and polymyositis (PM) are both immune-mediated inflammatory myopathies known to occur in paraneoplastic syndromes associated with a new diagnosis of malignancy, most commonly breast, ovarian, lung, pancreatic, stomach, colorectal, and Non-Hodgkin's lymphoma1 in DM and breast, lung, bladder cancer, and Non-Hodgkin's lymphoma in PM. 2,3,4 While inflammatory markers such as creatine kinase (CK) may be elevated with either DM or PM, marked elevation is rare. Herein, we report a case of newly diagnosed pancreatic cancer presenting with inflammatory myopathy and marked CK elevation. We review the frequency of PM as a paraneoplastic syndrome, the association with marked CK elevation, and the association with pancreatic cancer.

3.
Rheumatol Int ; 40(10): 1739, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32666136

RESUMO

In the original article published, the name of the second author is incorrect.

4.
Rheumatol Int ; 40(10): 1733-1737, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32358641

RESUMO

IgG4-related disease (IgG4-RD) is an inflammatory and fibrosing disease which causes tumor-like swelling of organs and commonly mimics symptoms of malignancy. It has been increasing in prevalence in the last decade, but esophageal involvement remains rare. IgG4-RD was first known to involve certain organs, such as the pancreas. It has, since, been described as a systemic disease process. IgG4-RD should be considered in patients presenting with dysphagia. Initiation of appropriate treatment with corticosteroids can avoid unnecessary procedures and improve outcomes. The aim of this review is to discuss 17 cases of IgG4-RD of the esophagus. Literature review was conducted using NCBI database (PMC and PubMed filters) using the keywords "IgG4 disease," "sclerosing," "esophagus" and "gastrointestinal." The search was narrowed to include cases describing IgG4 disease of the esophagus using the same filters. Literature review identified 16 documented cases of IgG4-RD involving the esophagus. Upon literature review, it remains clear that it is extremely rare for IgG4-RD to affect the esophagus. Sixteen cases have been reported. We present a 17th case and discuss the implications of IgG4-RD. It is important to keep a broad differential diagnosis that includes IgG4-RD for patients presenting with dysphagia, especially when symptoms are refractory.


Assuntos
Doenças do Esôfago/patologia , Doença Relacionada a Imunoglobulina G4/complicações , Adolescente , Adulto , Idoso , Doenças do Esôfago/tratamento farmacológico , Doenças do Esôfago/etiologia , Feminino , Glucocorticoides/administração & dosagem , Humanos , Doença Relacionada a Imunoglobulina G4/tratamento farmacológico , Masculino , Pessoa de Meia-Idade , Prednisona/administração & dosagem , Adulto Jovem
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