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Hepatogastroenterology ; 47(32): 455-60, 2000.
Artigo em Inglês | MEDLINE | ID: mdl-10791212

RESUMO

BACKGROUND/AIMS: In alcohol abusers an alteration of responses to psychometric tests has been reported, even when clinical symptoms of hepatic encephalopathy (HE) are absent. Our research was intended to individualize a simple psychometric test, easy enough to be performed also at the patient's home, able to reveal an impending encephalopathy and, consequently, to facilitate earlier treatment. METHODOLOGY: Twenty-six consecutive male alcoholics were engaged and, after informed consent, the following schedule was applied: administration of a psychometric test, followed by a drawing of blood for the determination of many blood parameters. After 15 days of treatment to detoxicate patients, psychometric tests and blood examinations were repeated. RESULTS: The results confirmed that common blood examinations are not useful to monitor brain damage in chronic alcoholism, that a psychometric test is able to demonstrate a therapeutic improvement and that a positive and significant correlation has been observed between BBCA/AAA ratio and WAIS Score. CONCLUSIONS: These preliminary results suggest that it is possible to suspect dangerous biochemical changes by means of a simple psychometric test.


Assuntos
Encefalopatia Hepática/diagnóstico , Cirrose Hepática Alcoólica/diagnóstico , Escalas de Wechsler/estatística & dados numéricos , Adulto , Encefalopatia Hepática/psicologia , Humanos , Cirrose Hepática Alcoólica/psicologia , Testes de Função Hepática , Masculino , Pessoa de Meia-Idade , Psicometria , Fatores de Risco , Sensibilidade e Especificidade
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