A comprehensive overview of the frequency and the severity of injuries sustained by car occupants and subsequent implications in terms of injury prevention.

The objective of the paper is to give an overview of the road injuries issues in France in the 2010's by determining the frequency and the severity of injuries sustained by car occupants, and to infer the implications in terms of vehicule safety. Three types of analysis are conducted. First, we present a time series analysis at a macro statistical level showing a dramatic decrease of injured and fatally injured occupants in passenger cars compared to other modes of road transport. Secondly, we propose a descriptive statistical analysis of the injuries (frequency and severity) sustained by car occupants, by body regions, using the AIS. Finally we propose some insights into the effectiveness of some safety features. French National crash census (BAAC) is used for a general overview of injury frequencies and raw severity scores (fatal, hospitalized, slighty injured) in car crashes. In-depth crash investigations data are used to specify the body regions and the severity of the injuries sustained by car occupants. Data show that car occupants mortality and morbidity decreased more over the last decade than other road modes: -58 % fatalities and -64 % hospitalized (compared to -39% and -55% for pedestrians, and -21% and -44% for motorcyclists for example). In crashes for which at least one person has been injured, 19 % of occupants are uninjured, 49 % of occupants sustain MAIS 1 injuries, 15 % MAIS2, 8% MAIS 3, and 9 % MAIS 4+. Regardless of seat belt use, the body regions most often injured are head, upper and lower extremities and thorax. However, at least two third up to 92% of involved persons sustain no injury at each of these body regions. The frequency of severe injuries is low, often less than 10 % and concern head and thorax mainly. Finally, the frequency and severity of injuries decrease for belted occupants in newer cars compared to older cars, whatever body regions. The frequency of severe injuries decreased by almost 50 % in these newer cars.

How Safe is Vehicle Safety? The Contribution of Vehicle Technologies to the Reduction in Road Casualties in France from 2000 to 2010.

In France, over the last 10 years, road fatalities have decreased dramatically by 48%. This reduction is somewhat close to the target fixed by the European Commision in 2001 for the whole of Europe (-50 %). According to the French govnerment, 75% of this reduction was due to the implementation of automatic speed cameras on the roadsides from 2003 onwards. Yet, during this period, there was also a significantly increase in safety technology, new regulations in front and side impacts, and developments in Euro NCAP to improve passive safety in the vehicles. This paper set out to estimate the extent that vehicle safety technologies contributed to the road safety benefits over this decade. Using a combination of databases and fitment rates, the number of fatalities and hospitalized injuries saved in passenger car crashes was estimated for a number of safety technologies, individually and as a package including a 5 star EuroNCAP rating. The additional benefits from other public safety measures were also similarly estimated. The results showed that overall safety measures during this decade saved 240,676 fatalities + serious injuries, of which 173,663 were car occupants. Of these, 27,365 car occupants and 1,083 pedestrian savings could be attributed directly to vehicle safety improvements (11% overall). It was concluded that while public safety measures were responsible for the majority of the savings, enhanced vehicle safety technologies also made a significant improvement in the road toll in France during the last decade. As the take-up rate for these technologies improves, is expected to continue to provide even more benefits in the next 10-year period.

The evaluation of the safety benefits of combined passive and on-board active safety applications.

One of the objectives of the European TRACE project (TRaffic Accident Causation in Europe, 2006-2008) was to estimate the proportion of injury accidents that could be avoided and/or the proportion of injury accidents where the severity could be mitigated for on-the-market safety applications, if 100 % of the car fleet would be equipped with them. We have selected for evaluation the Electronic Stability Control (ESC) and the Emergency Brake Assist (EBA) applications. As for passive safety systems, recent cars are designed to offer overall safety protection. Car structure, load limiters, front airbags, side airbags, knee airbags, pretensioners, padding and non aggressive structures in the door panel, the dashboard, the windshield, the seats, and the head rest also contribute to applying more protection. The whole safety package is very difficult to evaluate separately, one element independently segmented from the others. We decided to consider evaluating the effectiveness of the whole passive safety package, This package,, for the sake of simplicity, was the number of stars awarded at the Euro NCAP testing. The challenges were to compare the effectiveness of some safety configuration SC I, with the effectiveness of a different safety configuration SC II. A safety configuration is understood as a package of safety functions. Ten comparisons have been carried out such as the evaluation of the safety benefit of a fifth star given that the car has four stars and an EBA. The main outcome of this analysis is that any addition of a passive or active safety function selected in this analysis is producing increased safety benefits. For example, if all cars were five stars fitted with EBA and ESC, instead of four stars without ESC and EBA, injury accidents would be reduced by 47.2% for severe injuries and 69.5% for fatal injuries.

The potential for automatic crash notification systems to reduce road fatalities.

This predictive study investigated the effectiveness of Automatic Crash Notification (ACN) systems in reducing road fatalities, due to enabling faster emergency medical services (EMS) notification times, and therefore, the earlier provision of treatment. The cost-effectiveness associated with fleet installation of ACN systems in Australia was also evaluated. A range of data sources were used to identify the range of road fatalities that ACN systems could potentially mitigate, with urban and rural crashes analyzed separately, due to the average EMS notification time being slower for rural areas. It was established that ACN would provide an average crash-to-EMS notification time of one minute, which represented a three minute reduction in the total crash-to-hospital time for urban areas, with the corresponding reduction for rural areas being six minutes. Calculations revealed that these reductions would save an estimated 104 fatalities on Australian roads per annum (41 urban and 63 rural), assuming all vehicles were fitted with ACN. This corresponds to almost 11% of all passenger vehicle occupant fatalities. Despite the potential for ACN to significantly influence the Australian road toll, the benefit-cost-ratio analysis indicated that without government support, the systems are unlikely to be a cost-effective option for mandatory installation in all registered passenger vehicles. It was also recommended, however, that the benefits of ACN systems should be further investigated, in order to better establish their potential to increase road safety.

Traumatic rupture of thoracic aorta in real-world motor vehicle crashes.

OBJECTIVE: Traumatic rupture of thoracic aorta (TRA) was reported in the literature to be a major cause of death in motor vehicle crashes. This study aims at evaluating the most relevant risk factors of TRA. It also aims at analyzing the types of TRA as a function of car crash conditions and rib cage fractures. METHODS: In-depth crash data collected from 1998 to 2006 as part of the Co-operative Crash Injury Study (CCIS) were retrospectively investigated to assess frontal, near-side, and far-side injury risks. This database includes 15,074 occupants with individual detailed autopsy reports. Multivariate statistical analyses were performed. The influence of the following variables on TRA occurrence was studied: gender and age of the involved occupant, ETS, compartment intrusion, and restraint system. Features of TRA and rib cage fractures were described thanks to autopsy data. RESULTS: Although TRA occurred in only 1.2% of all occupants, TRA victims accounted for 21.4% of all fatalities. The incidence of TRA was found twice higher in side impacts (2.4%) than in frontal ones (1.1%). TRA injury risk increased with ETS, intrusion, and age and decreased with the absence of intrusion regardless of the impact direction. It also decreased for belted occupants in frontal impacts. Except for the site of injury, the TRA features were similar whatever the crash conditions. The multiple ribs fractures were the most common injuries associated with TRA (79.1%) and TRA victims with uninjured or slightly injured (AIS 1) rib cage were significantly younger (p < 0.0001) than other TRA victims. Whatever the impact type, the TRA victims sustained mostly bilateral rib fractures (68%). Results also emphasized a close relationship between the principal direction of force and the body side with more fractured ribs. However, whatever the impact type, the aortic injury site or the side of the thorax, fractures concerned mainly the 2nd up to the 7th ribs of TRA victims. CONCLUSIONS: This study emphasized four main variables influencing the TRA occurrence: ETS, compartment intrusion, age, and seat belt use. The results suggested that the injury site may be different depending on the occupant or the impact type. However, the typical TRA, i.e., a partial or complete aorta transection within the peri-isthmic region, affected any occupant independently of age and impact type. The high frequency of bilateral rib cage fractures observed in TRA victims and the significant influence of intrusion on TRA occurrence emphasized that the aortic injury mechanism mainly involves a severe direct chest impact or compression.

Can emergency physicians identify a high mortality subgroup of patients with sepsis: role of procalcitonin.

OBJECTIVE: To assess the potential role of procalcitonin and tumor necrosis factor-alpha, interleukin-6 and interleukin-8, in the prognosis of patients with sepsis. DESIGN: Prospective study. SETTING: The emergency unit of a teaching hospital. PATIENTS: We included 131 patients with sepsis: 15 (12%) with septic shock, 20 (15%) with severe sepsis and 96 (73%) with sepsis. MEASUREMENTS AND MAIN RESULTS: Out of the 131 patients, 112 (85.5%) survived and 19 (14.5%) died. These two groups of patients differed with regard to simplified acute physiology score II, severity of infectious disease and underlying disease, bacteremia and type of microorganisms. The mean serum levels of tumor necrosis factor, interleukin-6, interleukin-8, procalcitonin and lactates at study entry were higher in nonsurvivors than in survivors. Multivariate regression analysis showed the most significant of these variables to be serum procalcitonin level (P=0.0007), simplified acute physiology score II (P=0.03) and serum lactate level (P=0.03). Using a model incorporating these three variables, with a cut-off value corresponding to a 15% probability of predicting mortality, death could be correctly predicted in 99.5% of cases and survival in 95%. This cut-off value allowed us to maximize the prediction of death. When serum procalcitonin levels were not taken into account, the best model included simplified acute physiology score II and serum lactate and interleukin-6 levels, but the rate of correct prediction of death then dropped to 84%. CONCLUSIONS: Stepwise multivariate logistic regression analysis showed serum procalcitonin level to be a valuable marker of sepsis severity, compared with the 15 other clinical, biochemical and bacteriologic variables tested.

[Troponin I values during rhabdomyolysis in elderly patients admitted to the emergency department]. / Valeurs de la troponine I au cours des rhabdomyolyses chez les personnes âgées admises aux urgences.

OBJECTIVE: The objective of this study was to assess the utility of determining serum cardiac troponin I (TcI) levels in the elderly. METHODS: During the nine-month study period, all patients older than 70 years admitted to the emergency department presenting rhabdomyolysis (defined by creatine kinase>500 IU/L) were included in this prospective descriptive study, except for those with acute coronary syndrome or pulmonary embolism. Patients were classified into two groups according to their serum TcI level:>0.15 or0.15 ng/mL group and 37 in the other group. Clinical and laboratory indicators were similar in the two groups. In contrast, significantly more patients in the TcI>0.15 ng/mL group had been treated with a curative dose of heparin (14 versus 2, p=0.01). This difference between the two groups was noted in both the emergency department and other hospital units. Serum TcI levels were not correlated with creatine kinase levels. Concordance between emergency department diagnosis and discharge diagnosis was 95%. No patient was discharged with a diagnosis of acute coronary syndrome; one patient, with a serum TcI level0. 15 ng/mL group versus 8% in the other group). Mortality at six months was higher among patients with an elevated serum TcI level, but the difference was not significant (23% versus 8%, p=0.07). CONCLUSION: This study indicated a trend toward higher mortality among patients with elevated serum TcI levels, although the factors underlying these increased concentrations remain unclear.

Is electronic stability program effective on French roads?

This paper proposes an evaluation of the effectiveness of the electronic stability program (ESP) in terms of reduction of injury accidents in France. The method consists of 3 steps: The identification, in the French National injury accident census, of accident-involved cars for which the determination of whether or not the car was fitted with ESP is possible. A sampler of 136 cars involved in injury accidents occurred in 2000, 2001, 2002 and 2003 was then selected. But we had to restrict the analysis to only 588 Renalut Laguna's. The identification of accident situations for which we can determine whether or not ESP is pertinent ( for example ESP is pertinent for loss of control accidents whilst it is not for cars pulling out of a junction). The calculation, via a logistic regression, of the relative risk of being involved in an ESP-pertinent accident for ESP equipped cars versus unequipped cars, divided by the relative risk of being involved in a non-ESP-pertinent accident for ESP equipped cars versus unequipped cars. This relative risk is assumed to be the best estimator of ESP effectiveness. The arguments for such a method, effectiveness indicator and implicit hypothesis are presented and discussed in the paper. Based on a few assumptions, ESP is proved to be likely effective. Currently, the relative risk of being involved in an ESP-pertinent accident for ESP-equipped cars is lower (-44%, although not statistically significant) than for other cars.

An evaluation of the effectiveness of the supervised driver-training system in France.

This paper presents an evaluation of the effectiveness of the French Apprentissage Anticipé de la Conduite (AAC), which is an optional initial driver training that seeks to reduce accident risk by novice drivers. The effectiveness of the AAC is estimated using a Case-Control study (521 Cases and 624 Controls) and the adjusted Odds ratio (AAC versus regular) from a multivariate logistic regression. Thirteen risk factors are retained as explanatory variables in the regression. An Odds ratio of 0.9 indicates a non-significant reduction in accident involvement of AAC participants in the two years following the acquisition of their driver's license. The discussion addresses the possible reasons underlying the lack of result, e.g. an absence of varied experience during the AAC period and possible undesirable effects under supervision such as a partial delegation of responsibility for driving tasks by the young driver to the supervisor. Our recommendations include that AAC be integrated into a gradual licensing scheme, and should focus on the gradual acquisition of various driving experiences (in terms of variety of driving situations).