RESUMO
Clouston's syndrome is an ectodermal dysplasia characterized by dystrophic nails, alopecia, and palmoplantar hyperkeratosis. Alopecia is due to decrease in number and degree of maturation of the hair follicles. Tretinoin is a mitogen by itself and also enhances the absorption of minoxidil which acts by enlarging the miniaturized hair follicles. We report a case of alopecia in Clouston's syndrome who responded to treatment with topical minoxidil and tretinoin.
Assuntos
Alopecia/tratamento farmacológico , Alopecia/etiologia , Displasia Ectodérmica/complicações , Minoxidil/administração & dosagem , Tretinoína/administração & dosagem , Administração Tópica , Criança , Fármacos Dermatológicos/administração & dosagem , Quimioterapia Combinada , Cabelo/efeitos dos fármacos , Cabelo/crescimento & desenvolvimento , Humanos , MasculinoRESUMO
Menopause is a process, either naturally or medically induced, that occurs in nearly all women at some point in life. Some of the most commonly reported symptoms associated with menopause are hot flushes/flashes, fatigue, headaches, irritability, insomnia, and depression. These symptoms overlap with symptoms commonly reported in Traumatic Brain Injury (TBI) as well as postconcussive syndrome. This overlap between symptoms commonly associated with menopause and neuropsychological conditions makes it necessary to have the base rates of these symptoms and conditions available. The purpose of the present review was to consolidate the clinical literature on the most commonly reported menopausal symptoms and to calculate the base rates associated with these symptoms.