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Head Neck ; 34(7): 981-4, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21853501

RESUMO

BACKGROUND: Pediatric jaw osteosarcoma is uncommon, and data are scarce regarding clinical presentation, prognostic factors, and outcome. METHODS: A single-institution medical record review from 1983 to 2008 for 12 patients age ≤ 21 years was undertaken for this study. RESULTS: Median diagnosis age was 16.3 years (range, 6.3-21.9). Nine patients had mandible tumors. Osteoblastic subtype was most common (4 patients). Most tumors were large (ie, T2; n = 8) and high-grade (n = 8). Treatment characteristics were varied. Median follow-up was 27.1 months (range, 8-252 months). Five patients had tumor necrosis <80% after chemotherapy. No deaths were observed. CONCLUSION: Jaw osteosarcoma outcome is better compared to extremity osteosarcoma, but further study is required regarding clinical prognostic factors.


Assuntos
Neoplasias Maxilomandibulares/terapia , Osteossarcoma/terapia , Adolescente , Criança , Terapia Combinada , Feminino , Seguimentos , Humanos , Neoplasias Maxilomandibulares/patologia , Masculino , Gradação de Tumores , Osteossarcoma/patologia , Prognóstico , Resultado do Tratamento , Adulto Jovem
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