RESUMO
The authors report the observation of a lethal midline granuloma in a 43 years old man, at first seen with repeated left sinusitis disease, the histo-pathological study of a biopsy of the external middle third of the left side of the nose made the diagnosis of midline lethal granuloma, classically called Stewart granuloma by french authors. General Medical Investigations to find some peripheral extension, done in specialized services were negative, Epstein Barr DNA was not found by the immuno-histochemical investigations and so don't prove the filiation of this case with angiocentric T cell immunoproliferative lesion. By the light of this observation and of a literature review, the authors debate about the difficulty of diagnosis and about the relations with the other granulomatosis lesions of the face, non Hodgkins' lymphoma and angiocentric T cell immuno-proliferative lesions.
Assuntos
Granuloma Letal da Linha Média/complicações , Linfoma de Células T/complicações , Neoplasias Nasais/complicações , Neoplasias dos Seios Paranasais/complicações , Adulto , Granuloma Letal da Linha Média/patologia , Humanos , Linfoma de Células T/patologia , Masculino , Neoplasias Nasais/patologia , Neoplasias dos Seios Paranasais/patologiaRESUMO
Temporal arteritis is one of the localisation of the giant cell arteritis. The involvement of the female genital tract had been rarely reported with only 16 cases in the literature. We report 3 cases revealed by a tumor of the genital tract. Histologic features are found in the vessels of ovaries, fallopian tubes and myometrium. Only one patient had symptoms suggestive of temporal arteritis.
Assuntos
Genitália Feminina/irrigação sanguínea , Arterite de Células Gigantes/complicações , Idoso , Feminino , Humanos , Leiomioma/etiologia , Pessoa de Meia-Idade , Cistos Ovarianos/etiologia , Neoplasias Uterinas/etiologiaRESUMO
Three cases of granulomatous nephropathy are reported. In two patients this was definitely related to a true renal sarcoidosis, while the third case raised the problem of the significance of an "isolated sarcoidosis nodule". The authors discuss the frequency, clinical symptoms, and pathological appearances of these renal lesions which reveal the presence of sarcoidosis, as well as the relationship between renal insufficiency and the parenchymatous lesions observed, and therapy.